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  2. Mybpc3 - myosin binding protein C, cardiac Gene

Mybpc3 - myosin binding protein C, cardiac Gene

种属: Mus musculus

基因 ID: 17868 | 基因类型: protein coding

关于 Mybpc3

功能概要

Enables Myosin heavy chain binding activity. Acts upstream of or within several processes, including actin Cytoskeleton organization; cardiac muscle contraction; and regulation of heart rate. Located in A band. Is expressed in several structures, including alimentary system; cardiovascular system; face; liver; and skeleton. Used to study hypertrophic cardiomyopathy 4. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 4. Orthologous to human MYBPC3 (Myosin binding protein C3). [provided by Alliance of Genome Resources, Apr 2022]

Mybpc3 基因产物(1)

mRNA Protein Name
NM_008653.2 NP_032679.2 myosin-binding protein C, cardiac-type
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables myosin heavy chain binding IPI
IPI: 通过物理相互作用推断
17075052 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17075052 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cardiac muscle contraction IMP
IMP: 通过突变表型推断
16224063 MGI
acts upstream of or within heart morphogenesis IMP
IMP: 通过突变表型推断
10532952 MGI
acts upstream of or within myosin filament assembly IMP
IMP: 通过突变表型推断
17254601 MGI
acts upstream of or within regulation of heart contraction IMP
IMP: 通过突变表型推断
14500336 MGI
acts upstream of or within regulation of heart rate IMP
IMP: 通过突变表型推断
10532952 MGI
acts upstream of or within sarcomere organization IMP
IMP: 通过突变表型推断
16224063 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in A band IDA
IDA: 通过直接分析推断
10532952 MGI
located in myofibril IDA
IDA: 通过直接分析推断
10545522 MGI
located in sarcomere IDA
IDA: 通过直接分析推断
17075052 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

myosin-binding protein C, cardiac-type

cardiac C-protein

cardiac MyBP-C

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mybpc3 NCBI NCBI:4607