2. Gene
  3. Myoc - myocilin Gene

Myoc - myocilin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: TIGR; GLC1A

基因 ID: 17926 | 基因类型: protein coding

关于 Myoc

功能概要

Enables receptor tyrosine kinase binding activity. Involved in several processes, including ERBB2-ERBB3 signaling pathway; neurogenesis; and skeletal muscle hypertrophy. Located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and node of Ranvier. Is expressed in several structures, including brain; eye; genitourinary system; lung; and meninges. Used to study open-angle glaucoma. Human ortholog(s) of this gene implicated in juvenile glaucoma; low tension glaucoma; ocular hypertension; open-angle glaucoma; and primary open angle glaucoma. Orthologous to human MYOC (myocilin). [provided by Alliance of Genome Resources, Apr 2022]

Myoc 基因产物(1)

mRNA Protein Name
NM_010865.3 NP_034995.3 myocilin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12019210 MGI
enables receptor tyrosine kinase binding IPI
IPI: 通过物理相互作用推断
23897819 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ERBB2-ERBB3 signaling pathway IDA
IDA: 通过直接分析推断
23897819 MGI
involved in bone development IDA
IDA: 通过直接分析推断
23629661 MGI
involved in clustering of voltage-gated sodium channels IMP
IMP: 通过突变表型推断
23897819 MGI
involved in myelination in peripheral nervous system IMP
IMP: 通过突变表型推断
23897819 MGI
involved in osteoblast differentiation IDA
IDA: 通过直接分析推断
23629661 MGI
involved in skeletal muscle hypertrophy IDA
IDA: 通过直接分析推断
22371502 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
23629661 MGI
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
23629661 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
12019210 MGI
located in node of Ranvier IDA
IDA: 通过直接分析推断
23897819 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

myocilin

trabecular meshwork-induced glucocorticoid response protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08954 MYOC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20300 Myoc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26808 Myoc Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Myoc NCBI NCBI:4653
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