2. Gene
  3. Nfia - nuclear factor I/A Gene

Nfia - nuclear factor I/A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CTF; NF1A; NF1-A; 1110047K16Rik; 9430022M17Rik

基因 ID: 18027 | 基因类型: protein coding

关于 Nfia

功能概要

Enables DNA binding activity and chromatin binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within synapse maturation and ureter development. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in NFIA-related disorder. Orthologous to human NFIA (nuclear factor I A). [provided by Alliance of Genome Resources, Apr 2022]

Nfia 基因产物(3)

mRNA Protein Name
NM_001122952.1 NP_001116424.1 nuclear factor 1 A-type isoform 1
NM_001122953.1 NP_001116425.1 nuclear factor 1 A-type isoform 3
NM_010905.3 NP_035035.1 nuclear factor 1 A-type isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
12955085 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
23407945 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in BMP signaling pathway IMP
IMP: 通过突变表型推断
29247144 MGI
involved in cartilage development IMP
IMP: 通过突变表型推断
29247144 MGI
involved in cell morphogenesis IMP
IMP: 通过突变表型推断
29247144 MGI
acts upstream of or within cell quiescence IMP
IMP: 通过突变表型推断
33004674 MGI
acts upstream of or within exit from mitosis IMP
IMP: 通过突变表型推断
31128945 MGI
involved in gene expression IGI
IGI: 通过遗传相互作用推断
29106906 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
31128945 MGI
acts upstream of or within generation of neurons IMP
IMP: 通过突变表型推断
33004674 MGI
acts upstream of or within glial cell fate specification IMP
IMP: 通过突变表型推断
31128945 MGI
acts upstream of or within glial cell proliferation IMP
IMP: 通过突变表型推断
31128945 MGI
involved in limb morphogenesis IMP
IMP: 通过突变表型推断
29247144 MGI
acts upstream of or within neural precursor cell proliferation IMP
IMP: 通过突变表型推断
31128945 MGI
acts upstream of or within neurogenesis IMP
IMP: 通过突变表型推断
31128945 MGI
acts upstream of or within neuron fate specification IMP
IMP: 通过突变表型推断
31128945 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9056636 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19706729 MGI
acts upstream of or within response to wounding IMP
IMP: 通过突变表型推断
33004674 MGI
acts upstream of or within retina development in camera-type eye IMP
IMP: 通过突变表型推断
31128945 MGI
acts upstream of or within synapse maturation IMP
IMP: 通过突变表型推断
23407945 MGI
acts upstream of or within ureter development IMP
IMP: 通过突变表型推断
17530927 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
8306889 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear factor 1 A-type

CCAAT-box-binding transcription factor

TGGCA-binding protein

nuclear factor 1/A

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09249 NFIA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20782 Nfia Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27296 Nfia Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nfia NCBI NCBI:4774
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