1. Gene
  2. Npr3 - natriuretic peptide receptor 3 Gene

Npr3 - natriuretic peptide receptor 3 Gene

种属: Mus musculus

同用名: lgj; EF-2; stri; ANP-C; NPR-C; ANPR-C

基因 ID: 18162 | 基因类型: protein coding

关于 Npr3

功能概要

Predicted to enable several functions, including chloride ion binding activity; peptide receptor activity; and protein homodimerization activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; osteoclast proliferation; and positive regulation of urine volume. Predicted to be located in membrane. Predicted to be part of protein-containing complex. Is expressed in several structures, including central nervous system; genitourinary system; gut; heart and pericardium; and lung. Used to study bone disease. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human NPR3 (natriuretic peptide receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Npr3 基因产物(6)

mRNA Protein Name
NM_001039181.2 NP_001034270.1 atrial natriuretic peptide receptor 3 isoform b precursor
NM_001286395.2 NP_001273324.1 atrial natriuretic peptide receptor 3 isoform c
NM_001411434.1 NP_001398363.1 atrial natriuretic peptide receptor 3 isoform c
NM_001411435.1 NP_001398364.1 atrial natriuretic peptide receptor 3 isoform d
NM_001411436.1 NP_001398365.1 atrial natriuretic peptide receptor 3 isoform d
NM_008728.3 NP_032754.2 atrial natriuretic peptide receptor 3 isoform a precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in angiogenesis IMP
IMP: 通过突变表型推断
30586761 MGI
involved in blood vessel remodeling IMP
IMP: 通过突变表型推断
30586761 MGI
involved in negative regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
22307324 MGI
involved in osteoclast proliferation IMP
IMP: 通过突变表型推断
10377427 MGI
involved in positive regulation of urine volume IMP
IMP: 通过突变表型推断
10377427 MGI
involved in regulation of blood pressure IMP
IMP: 通过突变表型推断
10377427 MGI
involved in regulation of osteoblast proliferation IMP
IMP: 通过突变表型推断
10377427 MGI
involved in response to ischemia IMP
IMP: 通过突变表型推断
30586761 MGI
involved in skeletal system development IDA
IDA: 通过直接分析推断
10377427 MGI
involved in skeletal system development IMP
IMP: 通过突变表型推断
10377427 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

atrial natriuretic peptide receptor 3

Nppc receptor

atrial natriuretic peptide clearance receptor

atrial natriuretic peptide receptor type C

longjohn

strigosus

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Npr3 NCBI NCBI:4883