1. Gene
  2. Fxyd5 - FXYD domain-containing ion transport regulator 5 Gene

Fxyd5 - FXYD domain-containing ion transport regulator 5 Gene

种属: Mus musculus

同用名: RIC; EF-8; Oit2

基因 ID: 18301 | 基因类型: protein coding

关于 Fxyd5

功能概要

This gene encodes a precursor protein that is member of the FXYD family of transmembrane glycoproteins. Like most members of the FXYD family, the encoded protein is a subunit of the sodium-potassium adenosine triphosphatase pump. FXYD family members have tissue-specific expression and differentially regulate the activity of this pump. The protein encoded by this gene also plays a role in cell adhesion and motility. The orthologous human protein inhibits epithelial Cadherin, a calcium-dependent adhesion protein and is associated with Cancer (promotes metastasis). Alternative splicing of this mouse gene results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Fxyd5 基因产物(4)

mRNA Protein Name
NM_001111073.2 NP_001104543.1 FXYD domain-containing ion transport regulator 5 isoform a precursor
NM_001287213.1 NP_001274142.1 FXYD domain-containing ion transport regulator 5 isoform a precursor
NM_001287217.1 NP_001274146.1 FXYD domain-containing ion transport regulator 5 isoform b precursor
NM_008761.4 NP_032787.1 FXYD domain-containing ion transport regulator 5 isoform a precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ion channel regulator activity IDA
IDA: 通过直接分析推断
16148001 MGI
enables potassium channel regulator activity IDA
IDA: 通过直接分析推断
16148001 MGI
enables sodium channel regulator activity IDA
IDA: 通过直接分析推断
16148001 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
16148001 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

FXYD domain-containing ion transport regulator 5

dysadherin

ion channel homolog RIC

oncoprotein induced transcript 2

oncoprotein-induced protein 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fxyd5 NCBI NCBI:53827