2. Gene
  3. Pfkfb1 - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Gene

Pfkfb1 - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PFK/FBPase 1

基因 ID: 18639 | 基因类型: protein coding

关于 Pfkfb1

功能概要

Predicted to enable several functions, including 6-phosphofructo-2-kinase activity; anion binding activity; and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in carbohydrate phosphorylation; fructose 2,6-bisphosphate metabolic process; and positive regulation of Glucokinase activity. Predicted to act upstream of or within phosphorylation. Predicted to be part of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex. Predicted to be active in cytosol. Orthologous to human PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pfkfb1 基因产物(8)

mRNA Protein Name
NM_001374170.1 NP_001361099.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 2
NM_001374171.1 NP_001361100.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 2
NM_001374172.1 NP_001361101.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 2
NM_001374173.1 NP_001361102.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1
NM_001374175.1 NP_001361104.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 3
NM_001411763.1 NP_001398692.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 2
NM_001411764.1 NP_001398693.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 4
NM_008824.4 NP_032850.1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fructose-2,6-bisphosphate 2-phosphatase activity IGI
IGI: 通过遗传相互作用推断
16155866 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of glycolytic process through fructose-6-phosphate IGI
IGI: 通过遗传相互作用推断
16155866 MGI
involved in negative regulation of glycolytic process through fructose-6-phosphate IMP
IMP: 通过突变表型推断
15331593 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

6PF-2-K/Fru-2,6-P2ase liver isozyme

PFK-2/FBPase-2 gene A

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101972 AZ-PFKFB3-67 Inhibitor 97.03% 否
HY-101971 AZ PFKFB3 26 Inhibitor 99.23% 否
HY-178367 PFKFB4-IN-1 99.91% 否
HY-101972A AZ-PFKFB3-67 quarterhydrate Inhibitor 99.0% 否
HY-RS10361 PFKFB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20187 Pfkfb1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26691 Pfkfb1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pfkfb1 NCBI NCBI:5207
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