2. Gene
  3. Septin4 - septin 4 Gene

Septin4 - septin 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Bh5; ARTS; Sept4; Pnutl2; Gm11492; hCDCREL-2

基因 ID: 18952 | 基因类型: protein coding

关于 Septin4

功能概要

Predicted to enable several functions, including GTP binding activity; GTPase activity; and magnesium ion binding activity. Involved in flagellated sperm motility; neuron migration; and spermatid differentiation. Acts upstream of or within brain development; sperm capacitation; and sperm mitochondrion organization. Located in several cellular components, including dendrite; perikaryon; and sperm annulus. Part of septin complex. Is expressed in several structures, including central nervous system; olfactory epithelium; and retina. Orthologous to human SEPTIN4 (septin 4). [provided by Alliance of Genome Resources, Apr 2022]

Septin4 基因产物(10)

mRNA Protein Name
NM_001284392.2 NP_001271321.1 septin-4 isoform 2
NM_001284394.2 NP_001271323.1 septin-4 isoform 3
NM_001284398.2 NP_001271327.1 septin-4 isoform 4
NM_001361936.2 NP_001348865.1 septin-4 isoform 5
NM_001368775.2 NP_001355704.1 septin-4 isoform 6
NM_001368776.2 NP_001355705.1 septin-4 isoform 7
NM_001368777.2 NP_001355706.1 septin-4 isoform 8
NM_001368778.2 NP_001355707.1 septin-4 isoform 9
NM_001368779.2 NP_001355708.1 septin-4 isoform 10
NM_011129.3 NP_035259.1 septin-4 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17296554 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within brain development IMP
IMP: 通过突变表型推断
16314519 MGI
involved in flagellated sperm motility IMP
IMP: 通过突变表型推断
15737930 MGI
involved in hematopoietic stem cell homeostasis IMP
IMP: 通过突变表型推断
20952537 MGI
involved in negative regulation of stem cell proliferation IMP
IMP: 通过突变表型推断
30389919 MGI
involved in neuron migration IMP
IMP: 通过突变表型推断
20181826 MGI
acts upstream of or within sperm capacitation IMP
IMP: 通过突变表型推断
15737931 MGI
acts upstream of or within sperm mitochondrion organization IMP
IMP: 通过突变表型推断
15737931 MGI
acts upstream of or within spermatid development IMP
IMP: 通过突变表型推断
15737931 MGI
involved in spermatid differentiation IMP
IMP: 通过突变表型推断
15737931 MGI
involved in tissue morphogenesis IMP
IMP: 通过突变表型推断
30389919 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
20181826 MGI
located in axon terminus IDA
IDA: 通过直接分析推断
17296554 MGI
located in cell projection IDA
IDA: 通过直接分析推断
11064363 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
20181826 MGI
located in dendrite IDA
IDA: 通过直接分析推断
20181826 MGI
located in motile cilium IMP
IMP: 通过突变表型推断
15737931 MGI
located in perikaryon IDA
IDA: 通过直接分析推断
20181826 MGI
part of septin complex IDA
IDA: 通过直接分析推断
18809578 MGI
located in sperm annulus IDA
IDA: 通过直接分析推断
15737930 MGI
located in sperm flagellum IDA
IDA: 通过直接分析推断
23976951 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

septin-4

CE5B3 beta

M-Septin

bradeion beta

brain protein H5

cell division control-related protein 2

cell division control-related protein 2b

peanut-like 2 homolog

peanut-like protein 2

septin H5

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12683 SEPTIN4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21254 Septin4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27771 Septin4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Septin4 NCBI NCBI:5414
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