2. Gene
  3. Ptprd - protein tyrosine phosphatase, receptor type, D Gene

Ptprd - protein tyrosine phosphatase, receptor type, D Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: R-PTP-delta; 1110002J03Rik; 3000002J10Rik; B230219D21Rik

基因 ID: 19266 | 基因类型: protein coding

关于 Ptprd

功能概要

Enables cell adhesion molecule binding activity and signaling receptor binding activity. Involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; nervous system development; and regulation of synapse assembly. Acts upstream of or within negative regulation of receptor signaling pathway via JAK-STAT and regulation of immune response. Located in glutamatergic synapse and hippocampal mossy fiber to CA3 synapse. Is integral component of presynaptic membrane. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PTPRD (protein tyrosine Phosphatase receptor type D). [provided by Alliance of Genome Resources, Apr 2022]

Ptprd 基因产物(7)

mRNA Protein Name
NM_001352628.1 NP_001339557.1 receptor-type tyrosine-protein phosphatase delta isoform 2 precursor
NM_001352629.1 NP_001339558.1 receptor-type tyrosine-protein phosphatase delta isoform 3 precursor
NM_001352630.1 NP_001339559.1 receptor-type tyrosine-protein phosphatase delta isoform 4 precursor
NM_001368991.1 NP_001355920.1 receptor-type tyrosine-protein phosphatase delta isoform 5 precursor
NM_001368992.1 NP_001355921.1 receptor-type tyrosine-protein phosphatase delta isoform 6 precursor
NM_001368993.1 NP_001355922.1 receptor-type tyrosine-protein phosphatase delta isoform 7 precursor
NM_011211.4 NP_035341.2 receptor-type tyrosine-protein phosphatase delta isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cell adhesion molecule binding IPI
IPI: 通过物理相互作用推断
21940441 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21940441 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
21940441 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
IDA: 通过直接分析推断
21940441 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
10856223 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
10856223 MGI
acts upstream of or within negative regulation of receptor signaling pathway via JAK-STAT IMP
IMP: 通过突变表型推断
24843164 MGI
involved in neuron differentiation IDA
IDA: 通过直接分析推断
21940441 MGI
involved in positive regulation of dendrite morphogenesis IMP
IMP: 通过突变表型推断
21940441 MGI
involved in positive regulation of dendritic spine morphogenesis IDA
IDA: 通过直接分析推断
21940441 MGI
involved in positive regulation of synapse assembly IDA
IDA: 通过直接分析推断
25908590 MGI
involved in presynaptic membrane assembly IDA
IDA: 通过直接分析推断
21940441 MGI
involved in presynaptic membrane assembly IMP
IMP: 通过突变表型推断
21940441 MGI
acts upstream of or within regulation of immune response IMP
IMP: 通过突变表型推断
24843164 MGI
involved in regulation of postsynaptic density assembly IDA
IDA: 通过直接分析推断
22357843 MGI
involved in regulation of postsynaptic density assembly IMP
IMP: 通过突变表型推断
22357843 MGI
involved in synaptic membrane adhesion IDA
IDA: 通过直接分析推断
21940441 MGI
involved in trans-synaptic signaling IDA
IDA: 通过直接分析推断
32347567 MGI
involved in trans-synaptic signaling IEP
IEP: 通过表达模式推断
32347567 MGI
involved in trans-synaptic signaling IMP
IMP: 通过突变表型推断
32347567 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
10856223 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
10856223 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
22357843 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
22357843 MGI
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: 通过直接分析推断
10856223 MGI
is active in hippocampal mossy fiber to CA3 synapse IMP
IMP: 通过突变表型推断
10856223 MGI
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
29024665 MGI
is active in presynaptic membrane IMP
IMP: 通过突变表型推断
32347567 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

receptor-type tyrosine-protein phosphatase delta

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-115496 7-BIA Inhibitor 98.0% 否
HY-RS11436 PTPRD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17557 Ptprd Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24015 Ptprd Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptprd NCBI NCBI:5789
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