LCTL - lactase like Gene

中文名称：乳糖酶样

种属: Homo sapiens

同用名: KLG; KLPH

关于 LCTL

功能概要

该基因编码家族 1 糖苷酶的成员。糖苷酶是水解糖苷键的酶，根据一级氨基酸序列分为多个家族。家族 1 的大多数成员有两个保守的谷氨酸残基，这是酶活性所必需的。该蛋白质的小鼠直系同源物已被表征，具有 N 末端信号肽、糖苷酶结构域、跨膜结构域和短胞质尾的结构域。它缺少一种对催化很重要的保守谷氨酸残基，其功能仍有待确定 (PMID: 12084582) 。可变剪接导致多个转录本变体。[RefSeq 提供，2013 年 6 月]

This gene encodes a member of family 1 glycosidases. Glycosidases are Enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, Glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]