2. Gene
  3. Rfx2 - regulatory factor X, 2 (influences HLA class II expression) Gene

Rfx2 - regulatory factor X, 2 (influences HLA class II expression) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 5430432H19Rik

基因 ID: 19725 | 基因类型: protein coding

关于 Rfx2

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in acrosome assembly; cilium assembly; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; liver; ovary; primitive streak; and sensory organ. Orthologous to human RFX2 (regulatory factor X2). [provided by Alliance of Genome Resources, Apr 2022]

Rfx2 基因产物(2)

mRNA Protein Name
NM_009056.3 NP_033082.1 DNA-binding protein RFX2 isoform 2
NM_027787.2 NP_082063.1 DNA-binding protein RFX2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
14743396 MGI
enables DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
26162102 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP
IMP: 通过突变表型推断
26162102 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
IMP: 通过突变表型推断
8289803 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acrosome assembly IMP
IMP: 通过突变表型推断
26162102 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
involved in cilium assembly IMP
IMP: 通过突变表型推断
26162102 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
14743396 MGI
involved in regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
26162102 MGI
involved in spermatid development IMP
IMP: 通过突变表型推断
26162102 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA-binding protein RFX2

regulatory factor X 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11880 RFX2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22299 Rfx2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28822 Rfx2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rfx2 NCBI NCBI:5990
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