2. Gene
  3. Rfx3 - regulatory factor X, 3 (influences HLA class II expression) Gene

Rfx3 - regulatory factor X, 3 (influences HLA class II expression) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MRFX3; C230093O12Rik

基因 ID: 19726 | 基因类型: protein coding

关于 Rfx3

功能概要

Enables DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Involved in several processes, including epithelial cilium movement involved in determination of left/right asymmetry; positive regulation of type B pancreatic cell development; and type B pancreatic cell maturation. Acts upstream of or within determination of left/right symmetry. Located in chromatin. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; genitourinary system; inner cell mass; pancreas; and sensory organ. Used to study visceral heterotaxy. Orthologous to human RFX3 (regulatory factor X3). [provided by Alliance of Genome Resources, Apr 2022]

Rfx3 基因产物(4)

mRNA Protein Name
NM_001166414.2 NP_001159886.1 transcription factor RFX3 isoform 1
NM_001360357.1 NP_001347286.1 transcription factor RFX3 isoform 2
NM_001360358.1 NP_001347287.1 transcription factor RFX3 isoform 3
NM_011265.3 NP_035395.2 transcription factor RFX3 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
20413507 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
20148032 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
24531968 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
19671664 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA-templated transcription IMP
IMP: 通过突变表型推断
19671664 MGI
involved in cell maturation IMP
IMP: 通过突变表型推断
20413507 MGI
involved in cilium assembly IMP
IMP: 通过突变表型推断
20413507 MGI
involved in cilium-dependent cell motility IMP
IMP: 通过突变表型推断
19671664 MGI
acts upstream of or within determination of left/right symmetry IMP
IMP: 通过突变表型推断
15121860 MGI
involved in endocrine pancreas development IMP
IMP: 通过突变表型推断
17229940 MGI
involved in epithelial cilium movement involved in determination of left/right asymmetry IMP
IMP: 通过突变表型推断
15121860 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
20413507 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
20413507 MGI
involved in positive regulation of type B pancreatic cell development IMP
IMP: 通过突变表型推断
20413507 MGI
involved in regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
15121860 MGI
involved in regulation of insulin secretion IMP
IMP: 通过突变表型推断
17229940 MGI
involved in type B pancreatic cell maturation IMP
IMP: 通过突变表型推断
20413507 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
20413507 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
20413507 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor RFX3

regulatory factor X 3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11881 RFX3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22300 Rfx3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28823 Rfx3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rfx3 NCBI NCBI:5991
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z