2. Gene
  3. Rrm2 - ribonucleotide reductase M2 Gene

Rrm2 - ribonucleotide reductase M2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: R2

基因 ID: 20135 | 基因类型: protein coding

关于 Rrm2

功能概要

Enables ferric iron binding activity and protein homodimerization activity. Contributes to ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Involved in deoxyribonucleotide biosynthetic process and protein heterotetramerization. Acts upstream of or within deoxyribonucleotide metabolic process. Part of ribonucleoside-diphosphate reductase complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human RRM2 (ribonucleotide reductase regulatory subunit M2). [provided by Alliance of Genome Resources, Apr 2022]

Rrm2 基因产物(1)

mRNA Protein Name
NM_009104.2 NP_033130.1 ribonucleoside-diphosphate reductase subunit M2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ferric iron binding IDA
IDA: 通过直接分析推断
8876648 MGI
enables identical protein binding IMP
IMP: 通过突变表型推断
8130196 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
8130196 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
8876648 MGI
contributes to ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IDA
IDA: 通过直接分析推断
8612737 MGI
enables ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IDA
IDA: 通过直接分析推断
16829694 MGI
contributes to ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IMP
IMP: 通过突变表型推断
2684652 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 2'-deoxyribonucleotide biosynthetic process IDA
IDA: 通过直接分析推断
12578384 MGI
acts upstream of blastocyst development IMP
IMP: 通过突变表型推断
26902285 MGI
involved in deoxyribonucleotide biosynthetic process IDA
IDA: 通过直接分析推断
19176520 MGI
acts upstream of or within deoxyribonucleotide metabolic process IDA
IDA: 通过直接分析推断
12655059 MGI
involved in protein heterotetramerization IPI
IPI: 通过物理相互作用推断
19176520 MGI
involved in ribonucleoside diphosphate metabolic process IDA
IDA: 通过直接分析推断
12578384 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of ribonucleoside-diphosphate reductase complex IDA
IDA: 通过直接分析推断
8876648 MGI
part of ribonucleoside-diphosphate reductase complex IMP
IMP: 通过突变表型推断
8130196 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ribonucleoside-diphosphate reductase subunit M2

ribonucleoside-diphosphate reductase M2 chain

ribonucleotide reductase small chain

ribonucleotide reductase small subunit

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-30272 Monobenzone 99.93% 否
HY-B2116 Osalmid Inhibitor 99.80% 否
Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N0527 Pentagalloylglucose 99.57% 否
HY-153898 rTRD01 Ligand 99.10% 否
HY-112358 GW8510 Inhibitor 99.04% 否
HY-RS12286 RRM2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS12287 RRM2B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16616 Rrm2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21746 Rrm2b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23051 Rrm2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28263 Rrm2b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rrm2 NCBI NCBI:6241
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