2. Gene
  3. Scx - scleraxis Gene

Scx - scleraxis Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Scl; Bhlha41

基因 ID: 20289 | 基因类型: protein coding

关于 Scx

功能概要

This gene encodes a basic helix-loop-helix type transcription factor involved in mesoderm and heart valve formation. The encoded protein is expressed during embryonic development of tendons and ligaments. The gene product regulates Collagen type I gene expression in cardiac fibroblasts and myofibroblasts, and it may play a role in myocardial remodeling. The protein is expressed in the scar area of the adult heart following myocardial infarction. [provided by RefSeq, Feb 2010]

Scx 基因产物(1)

mRNA Protein Name
NM_198885.3 NP_942588.1 basic helix-loop-helix transcription factor scleraxis
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
7743923 MGI
contributes to E-box binding IDA
IDA: 通过直接分析推断
19828133 MGI
enables E-box binding IDA
IDA: 通过直接分析推断
7743923 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
7743923 MGI
enables bHLH transcription factor binding IPI
IPI: 通过物理相互作用推断
19828133 MGI
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
17430895 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
7743923 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
9328840 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in BMP signaling pathway IMP
IMP: 通过突变表型推断
20059955 MGI
involved in DNA-templated transcription IDA
IDA: 通过直接分析推断
9328840 MGI
involved in cell differentiation IMP
IMP: 通过突变表型推断
18802027 MGI
involved in cellular response to BMP stimulus IEP
IEP: 通过表达模式推断
9328840 MGI
involved in cellular response to mechanical stimulus IEP
IEP: 通过表达模式推断
21625049 MGI
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: 通过表达模式推断
9328840 MGI
involved in chondrocyte differentiation IMP
IMP: 通过突变表型推断
20059955 MGI
involved in collagen fibril organization IMP
IMP: 通过突变表型推断
18802027 MGI
involved in deltoid tuberosity development IMP
IMP: 通过突变表型推断
17567668 MGI
involved in embryonic skeletal system development IEP
IEP: 通过表达模式推断
7743923 MGI
involved in endochondral ossification IMP
IMP: 通过突变表型推断
20059955 MGI
involved in face morphogenesis IEP
IEP: 通过表达模式推断
18498113 MGI
involved in heart valve formation IMP
IMP: 通过突变表型推断
18802027 MGI
involved in heart valve morphogenesis IMP
IMP: 通过突变表型推断
18802027 MGI
involved in mesoderm formation IMP
IMP: 通过突变表型推断
10477299 MGI
involved in negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
18802027 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
10477299 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
7743923 MGI
involved in positive regulation of cartilage development IMP
IMP: 通过突变表型推断
10477299 MGI
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
10477299 MGI
involved in positive regulation of collagen biosynthetic process IDA
IDA: 通过直接分析推断
19362560 MGI
involved in positive regulation of collagen biosynthetic process IMP
IMP: 通过突变表型推断
18802027 MGI
involved in positive regulation of gastrulation IMP
IMP: 通过突变表型推断
10477299 MGI
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
19362560 MGI
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
18802027 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
7743923 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
17430895 MGI
involved in regulation of cartilage development IMP
IMP: 通过突变表型推断
18802027 MGI
involved in sclerotome development IEP
IEP: 通过表达模式推断
7743923 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: 通过突变表型推断
22147266 MGI
involved in tendon cell differentiation IMP
IMP: 通过突变表型推断
17567668 MGI
involved in tendon development IMP
IMP: 通过突变表型推断
17567668 MGI
involved in tendon formation IMP
IMP: 通过突变表型推断
14568104 MGI
involved in tissue homeostasis IMP
IMP: 通过突变表型推断
18802027 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
19362560 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
19828133 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

basic helix-loop-helix transcription factor scleraxis

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-158231 Polyether F127 Diacrylate Activator / 否
HY-RS12574 SCX Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22084 Scx Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28604 Scx Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Scx NCBI NCBI:642658
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