2. Gene
  3. Spop - speckle-type BTB/POZ protein Gene

Spop - speckle-type BTB/POZ protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: TEF2; Pcif1

基因 ID: 20747 | 基因类型: protein coding

关于 Spop

功能概要

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Acts upstream of or within several processes, including glucose homeostasis; positive regulation of apoptotic process; and regulation of transcription, DNA-templated. Located in nuclear speck. Is expressed in lung; metanephros; and pancreas. Orthologous to human SPOP (speckle type BTB/POZ protein). [provided by Alliance of Genome Resources, Apr 2022]

Spop 基因产物(2)

mRNA Protein Name
NM_001359107.1 NP_001346036.1 speckle-type POZ protein
NM_025287.2 NP_079563.2 speckle-type POZ protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
19684112 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15121856 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within glucose homeostasis IGI
IGI: 通过遗传相互作用推断
20679732 MGI
acts upstream of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IGI
IGI: 通过遗传相互作用推断
20811152 MGI
acts upstream of or within negative regulation of DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
15121856 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15121856 MGI
acts upstream of or within positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IGI
IGI: 通过遗传相互作用推断
20811152 MGI
acts upstream of or within positive regulation of type B pancreatic cell apoptotic process IGI
IGI: 通过遗传相互作用推断
20679732 MGI
acts upstream of or within proteasome-mediated ubiquitin-dependent protein catabolic process IGI
IGI: 通过遗传相互作用推断
20811152 MGI
acts upstream of type B pancreatic cell apoptotic process IGI
IGI: 通过遗传相互作用推断
20679732 MGI
acts upstream of or within ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
19684112 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nuclear speck IDA
IDA: 通过直接分析推断
15121856 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

speckle-type POZ protein

HIB homolog 1

PDX-1 C-terminal-interacting factor 1

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-136938 NEO2734 Inhibitor 99.63% Phase 1
Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-122615 SPOP-IN-6b 99.56% 否
HY-122615B SPOP-IN-6b dihydrochloride Inhibitor 99.70% 否
HY-156382 SPOP-IN-1 Inhibitor 99.71% 否
HY-161251 SPOP-IN-2 91.00% 否
HY-176036 MS1262 98.61% 否
HY-175247 DDO-4033 Agonist / 否
HY-122615A SPOP-IN-6b hydrochloride Inhibitor / 否
HY-176035 MS479 Degrader / 否
HY-RS13700 SPOP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-176038 MS1262-C3-amide-C10-amine / 否
HY-RS16789 Spop Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23229 Spop Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spop NCBI NCBI:8405
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