2. Gene
  3. Brcc3 - BRCA1/BRCA2-containing complex, subunit 3 Gene

Brcc3 - BRCA1/BRCA2-containing complex, subunit 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: C6.1A

基因 ID: 210766 | 基因类型: protein coding

关于 Brcc3

功能概要

Predicted to enable enzyme regulator activity; peptidase activity; and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in several processes, including histone H2A K63-linked deubiquitination; mitotic G2 DNA damage checkpoint signaling; and positive regulation of DNA repair. Predicted to act upstream of or within response to X-ray. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of BRCA1-A complex; BRISC complex; and nuclear ubiquitin Ligase complex. Is expressed in bladder; male associated reproductive structure; testis; ureter; and urethra of male. Orthologous to human BRCC3 (BRCA1/BRCA2-containing complex subunit 3). [provided by Alliance of Genome Resources, Apr 2022]

Brcc3 基因产物(5)

mRNA Protein Name
NM_001166457.1 NP_001159929.1 lys-63-specific deubiquitinase BRCC36
NM_001166459.1 NP_001159931.1 lys-63-specific deubiquitinase BRCC36
NM_001358736.1 NP_001345665.1 lys-63-specific deubiquitinase BRCC36
NM_001358737.1 NP_001345666.1 lys-63-specific deubiquitinase BRCC36
NM_145956.4 NP_666068.1 lys-63-specific deubiquitinase BRCC36
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables metal-dependent deubiquitinase activity IDA
IDA: 通过直接分析推断
23246432 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22974638 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chromatin remodeling IDA
IDA: 通过直接分析推断
34180153 MGI
involved in positive regulation of NLRP3 inflammasome complex assembly IDA
IDA: 通过直接分析推断
23246432 MGI
involved in protein K63-linked deubiquitination IDA
IDA: 通过直接分析推断
23246432 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lys-63-specific deubiquitinase BRCC36

6.1A protein

BRCA1-A complex subunit BRCC36

BRCA1/BRCA2-containing complex subunit 36

BRISC complex subunit BRCC36

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01595 BRCC3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS03694 DEPDC1B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17602 Brcc3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24062 Brcc3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Brcc3 NCBI NCBI:79184
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