2. Gene
  3. Alkbh1 - alkB homolog 1, histone H2A dioxygenase Gene

Alkbh1 - alkB homolog 1, histone H2A dioxygenase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Abh; alkB; hABH; Alkbh; 2700073G19Rik

基因 ID: 211064 | 基因类型: protein coding

关于 Alkbh1

功能概要

Enables chemoattractant activity and oxidative DNA demethylase activity. Involved in DNA demethylation and tRNA demethylation. Acts upstream of or within several processes, including generation of neurons; negative regulation of neuron apoptotic process; and placenta development. Located in euchromatin. Is expressed in several structures, including branchial arch; central nervous system; gonad; hemolymphoid system gland; and limb bud. Orthologous to human ALKBH1 (alkB homolog 1, histone H2A dioxygenase). [provided by Alliance of Genome Resources, Apr 2022]

Alkbh1 基因产物(1)

mRNA Protein Name
NM_001102565.1 NP_001096035.1 nucleic acid dioxygenase ALKBH1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables broad specificity oxidative DNA demethylase activity IDA
IDA: 通过直接分析推断
27027282 MGI
enables chemoattractant activity IDA
IDA: 通过直接分析推断
16860792 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18163532 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell differentiation IMP
IMP: 通过突变表型推断
18163532 MGI
acts upstream of or within developmental growth IMP
IMP: 通过突变表型推断
18163532 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
18163532 MGI
acts upstream of or within negative regulation of neuron apoptotic process IDA
IDA: 通过直接分析推断
16860792 MGI
acts upstream of or within neuron migration IDA
IDA: 通过直接分析推断
16860792 MGI
acts upstream of or within neuron projection development IDA
IDA: 通过直接分析推断
16860792 MGI
acts upstream of or within placenta development IMP
IMP: 通过突变表型推断
18163532 MGI
involved in positive regulation of gene expression, epigenetic IDA
IDA: 通过直接分析推断
27027282 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
18163532 MGI
involved in regulation of translational initiation by tRNA modification IMP
IMP: 通过突变表型推断
27745969 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in euchromatin IDA
IDA: 通过直接分析推断
18163532 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nucleic acid dioxygenase ALKBH1

Alkylated DNA repair protein alkB homolog 1

DNA 6mA demethylase

DNA N6-methyl adenine demethylase ALKBH1

DNA demethylase ALKBH1

DNA lyase ABH1

DNA oxidative demethylase ALKBH1

alkB, alkylation repair homolog 1

alpha-ketoglutarate-dependent dioxygen

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-163385 ALKBH1-IN-1 Inhibitor 99.63% 否
HY-158998 ALKBH1-IN-2 99.16% 否
HY-W002065 4-Carboxypyrazole 99.71% 否
HY-169131 ALKBH1-IN-3 prodrug Activator 99.15% 否
HY-168044 ALKBH1-IN-3 Activator / 否
HY-RS00603 ALKBH1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18694 Alkbh1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25181 Alkbh1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Alkbh1 NCBI NCBI:8846
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