1. Gene
  2. Adamts2 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2 Gene

Adamts2 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2 Gene

种属: Mus musculus

同用名: pNPI; PCINP; PC I-NP; ADAM-TS2; ADAMTS-2; ADAM-TS 2

基因 ID: 216725 | 基因类型: protein coding

关于 Adamts2

功能概要

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin repeats) family of proteinases that is involved in the proteolytic processing of procollagens. The encoded protein precursor is proteolytically processed to generate a mature, zinc-dependent enzyme. Mice lacking the encoded protein develop abnormal lungs, fragile skin and male sterility. [provided by RefSeq, Aug 2015]

Adamts2 基因产物(1)

mRNA Protein Name
NM_175643.3 NP_783574.1 A disintegrin and metalloproteinase with thrombospondin motifs 2 preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptidase activity IDA
IDA: 通过直接分析推断
16556917 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within collagen fibril organization IMP
IMP: 通过突变表型推断
16556917 MGI
acts upstream of or within lung development IMP
IMP: 通过突变表型推断
16556917 MGI
acts upstream of or within protein processing IMP
IMP: 通过突变表型推断
16556917 MGI
acts upstream of or within skin development IMP
IMP: 通过突变表型推断
11284712 MGI
acts upstream of or within spermatogenesis IMP
IMP: 通过突变表型推断
11284712 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular matrix IDA
IDA: 通过直接分析推断
16556917 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

A disintegrin and metalloproteinase with thrombospondin motifs 2

a disintegrin and metalloproteinase with thrombospondin repeats

a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2

procollagen I/II amino propeptide-processing enzyme

procollagen N-endopeptidase

procollagen N-

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adamts2 NCBI NCBI:9509