2. Gene
  3. Sry - sex determining region of Chr Y Gene

Sry - sex determining region of Chr Y Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tdf; Tdy

基因 ID: 21674 | 基因类型: protein coding

关于 Sry

功能概要

Enables DNA binding activity, bending and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in male sex determination. Acts upstream of or within male gonad development; negative regulation of gene expression; and negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including brain; early conceptus; and genitourinary system. Human ortholog(s) of this gene implicated in 46,XX sex reversal 1; 46,XY sex reversal; and 46,XY sex reversal 1. Orthologous to human SRY (sex determining region Y). [provided by Alliance of Genome Resources, Apr 2022]

Sry 基因产物(1)

mRNA Protein Name
NM_011564.1 NP_035694.1 sex-determining region Y protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
8625802 MGI
enables DNA binding, bending IDA
IDA: 通过直接分析推断
7774816 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
22344693 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10410901 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within male gonad development IDA
IDA: 通过直接分析推断
19457926 MGI
involved in male gonad development IDA
IDA: 通过直接分析推断
33004521 MGI
involved in male sex determination IDA
IDA: 通过直接分析推断
33004521 MGI
acts upstream of or within male sex determination IGI
IGI: 通过遗传相互作用推断
15879091 MGI
acts upstream of or within negative regulation of gene expression IDA
IDA: 通过直接分析推断
11869290 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
19850934 MGI
involved in sex determination IDA
IDA: 通过直接分析推断
33004521 MGI
acts upstream of or within sex determination IGI
IGI: 通过遗传相互作用推断
9486644 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
15469996 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
22344693 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sex-determining region Y protein

testis determining-Y

testis-determining factor

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13801 SRY Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174539 Human SOX2 mRNA / 否
HY-RS21288 Sry Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23830 Sox9 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sry NCBI NCBI:6736
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