2. Gene
  3. Plscr1 - phospholipid scramblase 1 Gene

Plscr1 - phospholipid scramblase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Nor1; Tra1; Tra1a; Tra1b; Tras1; Tras2; MmTRA1a; MmTRA1b

基因 ID: 22038 | 基因类型: protein coding

关于 Plscr1

功能概要

Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; metal ion binding activity; and signaling receptor binding activity. Involved in several processes, including negative regulation of viral genome replication; phosphatidylserine biosynthetic process; and response to interferon-alpha. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; phosphatidylserine exposure on apoptotic cell surface; and positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Located in cytosol; nucleus; and plasma membrane. Is expressed in hindgut; midgut; renal calyx; and renal pelvis. Orthologous to human PLSCR1 (phospholipid scramblase 1). [provided by Alliance of Genome Resources, Apr 2022]

Plscr1 基因产物(2)

mRNA Protein Name
NM_001410453.1 NP_001397382.1 phospholipid scramblase 1
NM_011636.3 NP_035766.2 phospholipid scramblase 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32110987 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acute-phase response IEP
IEP: 通过表达模式推断
17590392 MGI
involved in cellular response to cytokine stimulus IEP
IEP: 通过表达模式推断
17590392 MGI
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
17590392 MGI
involved in defense response to virus IMP
IMP: 通过突变表型推断
15308695 MGI
involved in intrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
15863367 MGI
acts upstream of or within myeloid cell differentiation IMP
IMP: 通过突变表型推断
15328404 MGI
acts upstream of or within negative regulation of protein binding IDA
IDA: 通过直接分析推断
16611984 MGI
involved in negative regulation of viral genome replication IMP
IMP: 通过突变表型推断
15308695 MGI
involved in phosphatidylserine biosynthetic process IDA
IDA: 通过直接分析推断
12509439 MGI
acts upstream of or within phosphatidylserine exposure on apoptotic cell surface IDA
IDA: 通过直接分析推断
12509439 MGI
involved in phosphatidylserine exposure on apoptotic cell surface IMP
IMP: 通过突变表型推断
32110987 MGI
involved in plasma membrane phospholipid scrambling IDA
IDA: 通过直接分析推断
12509439 MGI
acts upstream of or within positive regulation of apoptotic process IGI
IGI: 通过遗传相互作用推断
16611984 MGI
involved in positive regulation of innate immune response IMP
IMP: 通过突变表型推断
15308695 MGI
acts upstream of or within positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage IDA
IDA: 通过直接分析推断
12509439 MGI
involved in response to interferon-alpha IMP
IMP: 通过突变表型推断
15308695 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
17590392 MGI
located in nucleus IDA
IDA: 通过直接分析推断
17590392 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
12509439 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phospholipid scramblase 1

PL scramblase 1

ca(2+)-dependent phospholipid scramblase 1

mg(2+)-dependent nuclease

transplantability-associated protein 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10741 PLSCR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18201 Plscr1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24677 Plscr1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Plscr1 NCBI NCBI:5359
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