2. Gene
  3. Ctr9 - CTR9 homolog, Paf1/RNA polymerase II complex component Gene

Ctr9 - CTR9 homolog, Paf1/RNA polymerase II complex component Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tsp; Tsbp; Sh2bp1; mKIAA0155

基因 ID: 22083 | 基因类型: protein coding

关于 Ctr9

功能概要

Enables SH2 domain binding activity. Involved in several processes, including cell surface receptor signaling pathway; histone H3-K4 trimethylation; and positive regulation of histone H3-K4 methylation. Acts upstream of or within blastocyst development and regulation of genetic imprinting. Located in nucleus and transcriptionally active chromatin. Part of Cdc73/Paf1 complex. Is expressed in cerebral cortex. Orthologous to human CTR9 (CTR9 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Apr 2022]

Ctr9 基因产物(1)

mRNA Protein Name
NM_009431.2 NP_033457.2 RNA polymerase-associated protein CTR9 homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SH2 domain binding IDA
IDA: 通过直接分析推断
8636124 MGI
contributes to protein binding IPI
IPI: 通过物理相互作用推断
27749823 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
8636124 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blastocyst growth IGI
IGI: 通过遗传相互作用推断
24036311 MGI
acts upstream of or within blastocyst growth IMP
IMP: 通过突变表型推断
24036311 MGI
acts upstream of or within blastocyst hatching IMP
IMP: 通过突变表型推断
27869233 MGI
involved in cell surface receptor signaling pathway via JAK-STAT IMP
IMP: 通过突变表型推断
17911113 MGI
involved in cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
17911113 MGI
involved in chromatin organization IMP
IMP: 通过突变表型推断
19345177 MGI
involved in endodermal cell fate commitment IMP
IMP: 通过突变表型推断
19345177 MGI
acts upstream of or within inner cell mass cell differentiation IMP
IMP: 通过突变表型推断
24036311 MGI
involved in interleukin-6-mediated signaling pathway IMP
IMP: 通过突变表型推断
17911113 MGI
acts upstream of or within negative regulation of gene expression, epigenetic IMP
IMP: 通过突变表型推断
24036311 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
19345177 MGI
involved in stem cell population maintenance IMP
IMP: 通过突变表型推断
19345177 MGI
acts upstream of or within trophectodermal cell differentiation IMP
IMP: 通过突变表型推断
24036311 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Cdc73/Paf1 complex IPI
IPI: 通过物理相互作用推断
27749823 MGI
located in euchromatin IDA
IDA: 通过直接分析推断
19345177 MGI
located in nucleus IDA
IDA: 通过直接分析推断
8636124 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

RNA polymerase-associated protein CTR9 homolog

Ctr9, Paf1/RNA polymerase II complex component, homolog

SH2 domain binding protein 1 (tetratricopeptide repeat containing)

SH2 domain-binding protein 1

TPR-containing, SH2-binding phosphoprotein of 150 kDa

p150TSP

tetratricopeptide repeat-containing,

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-160267 iPAF1C Activator 99.59% 否
HY-RS03316 CTR9 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22131 Ctr9 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28653 Ctr9 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ctr9 NCBI NCBI:9646
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