2. Gene
  3. Ezr - ezrin Gene

Ezr - ezrin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: p81; Vil2

基因 ID: 22350 | 基因类型: protein coding

关于 Ezr

功能概要

Enables disordered domain specific binding activity and protein C-terminus binding activity. Involved in several processes, including intestinal D-glucose absorption; positive regulation of protein localization to plasma membrane; and terminal web assembly. Acts upstream of or within establishment or maintenance of apical/basal cell polarity and receptor internalization. Located in several cellular components, including brush border; microvillus; and uropod. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human EZR (ezrin). [provided by Alliance of Genome Resources, Apr 2022]

Ezr 基因产物(1)

mRNA Protein Name
NM_009510.2 NP_033536.2 ezrin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables disordered domain specific binding IDA
IDA: 通过直接分析推断
18321067 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9472040 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within establishment or maintenance of apical/basal cell polarity IMP
IMP: 通过突变表型推断
15177033 MGI
involved in intestinal D-glucose absorption IGI
IGI: 通过遗传相互作用推断
22114352 MGI
NOT involved in microvillus assembly IGI
IGI: 通过遗传相互作用推断
22114352 MGI
involved in positive regulation of multicellular organism growth IGI
IGI: 通过遗传相互作用推断
22114352 MGI
involved in positive regulation of protein localization to plasma membrane IGI
IGI: 通过遗传相互作用推断
22114352 MGI
involved in postsynaptic actin cytoskeleton organization IDA
IDA: 通过直接分析推断
29720403 MGI
involved in postsynaptic actin cytoskeleton organization IMP
IMP: 通过突变表型推断
29720403 MGI
acts upstream of or within receptor internalization IMP
IMP: 通过突变表型推断
16365167 MGI
involved in regulation of microvillus length IGI
IGI: 通过遗传相互作用推断
22114352 MGI
involved in terminal web assembly IGI
IGI: 通过遗传相互作用推断
22114352 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical part of cell IDA
IDA: 通过直接分析推断
9890997 MGI
located in apical plasma membrane IDA
IDA: 通过直接分析推断
14625387 MGI
located in brush border IDA
IDA: 通过直接分析推断
22114352 MGI
located in ciliary basal body IDA
IDA: 通过直接分析推断
14996907 MGI
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
17122142 MGI
located in microvillus IDA
IDA: 通过直接分析推断
9472040 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
21377456 MGI
located in uropod IDA
IDA: 通过直接分析推断
11728336 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ezrin

cytovillin

villin-2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04623 EZR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19860 Ezr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26360 Ezr Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ezr NCBI NCBI:7430
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