2. Gene
  3. Wdr1 - WD repeat domain 1 Gene

Wdr1 - WD repeat domain 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Aip1; rede; D5Wsu185e

基因 ID: 22388 | 基因类型: protein coding

关于 Wdr1

功能概要

Predicted to enable actin filament binding activity. Involved in several processes, including Cytoskeleton organization; establishment of planar polarity of follicular epithelium; and platelet formation. Acts upstream of or within positive regulation of actin filament depolymerization; regulation of ventricular cardiac muscle cell membrane repolarization; and sarcomere organization. Located in myelin sheath. Is expressed in several structures, including genitourinary system; heart; pharynx mesenchyme; telencephalon; and trunk mesenchyme. Orthologous to human WDR1 (WD repeat domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Wdr1 基因产物(1)

mRNA Protein Name
NM_011715.3 NP_035845.1 WD repeat-containing protein 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within actin cytoskeleton organization IMP
IMP: 通过突变表型推断
24840128 MGI
involved in actin filament fragmentation IMP
IMP: 通过突变表型推断
25915128 MGI
involved in cortical cytoskeleton organization IMP
IMP: 通过突变表型推断
17515402 MGI
involved in establishment of planar polarity of follicular epithelium IMP
IMP: 通过突变表型推断
25915128 MGI
involved in neutrophil mediated immunity IMP
IMP: 通过突变表型推断
17515402 MGI
involved in neutrophil migration IMP
IMP: 通过突变表型推断
17515402 MGI
involved in platelet formation IMP
IMP: 通过突变表型推断
17515402 MGI
acts upstream of or within positive regulation of actin filament depolymerization IGI
IGI: 通过遗传相互作用推断
24840128 MGI
involved in regulation of cell shape IMP
IMP: 通过突变表型推断
25915128 MGI
acts upstream of or within regulation of ventricular cardiac muscle cell membrane repolarization IMP
IMP: 通过突变表型推断
24840128 MGI
acts upstream of or within sarcomere organization IMP
IMP: 通过突变表型推断
24840128 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
31171447 MGI
is active in synapse IDA
IDA: 通过直接分析推断
31171447 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

WD repeat-containing protein 1

WD40 repeat protein 1

actin-interacting protein 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15760 WDR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19974 Wdr1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26477 Wdr1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Wdr1 NCBI NCBI:9948
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