1. Gene
  2. Dmrt2 - doublesex and mab-3 related transcription factor 2 Gene

Dmrt2 - doublesex and mab-3 related transcription factor 2 Gene

种属: Mus musculus

同用名: Terra

基因 ID: 226049 | 基因类型: protein coding

关于 Dmrt2

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within embryonic skeletal system development; positive regulation of myotome development; and regulation of somitogenesis. Predicted to be active in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; limb; oral epithelium; and thymus primordium. Orthologous to human DMRT2 (doublesex and mab-3 related transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Dmrt2 基因产物(1)

mRNA Protein Name
NM_145831.3 NP_665830.1 doublesex- and mab-3-related transcription factor 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
17974128 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
17605809 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
17605809 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
17605809 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within embryonic skeletal system development IMP
IMP: 通过突变表型推断
16387292 MGI
NOT acts upstream of or within left/right pattern formation IMP
IMP: 通过突变表型推断
21203428 MGI
acts upstream of myotome development IMP
IMP: 通过突变表型推断
16387292 MGI
acts upstream of or within positive regulation of myotome development IMP
IMP: 通过突变表型推断
16387292 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
17974128 MGI
acts upstream of or within regulation of somitogenesis IGI
IGI: 通过遗传相互作用推断
17974128 MGI
acts upstream of or within regulation of somitogenesis IMP
IMP: 通过突变表型推断
17974128 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

doublesex- and mab-3-related transcription factor 2

doublesex-like 2 protein

terra homolog

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dmrt2 NCBI NCBI:10655