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  2. FOXJ3 - forkhead box J3 Gene

FOXJ3 - forkhead box J3 Gene

中文名称:叉头盒 J3

种属: Homo sapiens

基因 ID: 22887 | 基因类型: protein coding

关于 FOXJ3

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:42,176,548-42,335,880 (from NCBI)

This gene has 9 transcripts (splice variants), 161 orthologues and 42 paralogues. Ubiquitous expression in thyroid (RPKM 10.6), testis (RPKM 10.1) and 25 other tissues.

功能概要

启用 DNA 结合转录激活因子活性、RNA 聚合酶 II 特异性和序列特异性双链 DNA 结合活性。参与 RNA 聚合酶 II 对转录的正调控。预测是染色质的一部分。预计活跃于核心。 [由基因组资源联盟提供,2022 年 4 月]

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

FOXJ3 基因产物(4)

mRNA Protein Name
NM_001198850.2 NP_001185779.1 forkhead box protein J3 isoform 1
NM_001198851.2 NP_001185780.1 forkhead box protein J3 isoform 1
NM_001198852.2 NP_001185781.1 forkhead box protein J3 isoform 2
NM_014947.5 NP_055762.3 forkhead box protein J3 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
22740631 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
23332764 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
22740631 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

FOXJ3 蛋白结构

Forkhead

Forkhead: Forkhead domain (78 - 162)

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  • 622 a.a.
蛋白主名 其他名称

forkhead box protein J3

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta FOXJ3 VGNC VGNC:72596
Bos taurus FOXJ3 VGNC VGNC:29091
Rattus norvegicus FOXJ3 RGD RGD:1311770
Felis catus FOXJ3 VGNC VGNC:62338
Mus musculus FOXJ3 MGD MGI:2443432
Canis familiaris FOXJ3 VGNC VGNC:40956