2. Gene
  3. Kdm4a - lysine (K)-specific demethylase 4A Gene

Kdm4a - lysine (K)-specific demethylase 4A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Jmjd2; JHDM3A; Jmjd2a; mKIAA0677; D4Ertd222e

基因 ID: 230674 | 基因类型: protein coding

关于 Kdm4a

功能概要

Enables Histone Demethylase activity. Acts upstream of or within cardiac muscle hypertrophy in response to stress and negative regulation of histone H3-K9 trimethylation. Located in pericentric heterochromatin. Is expressed in several structures, including branchial arch; central nervous system; dorsal root ganglion; early conceptus; and genitourinary system. Orthologous to human KDM4A (lysine demethylase 4A). [provided by Alliance of Genome Resources, Apr 2022]

Kdm4a 基因产物(2)

mRNA Protein Name
NM_001161823.1 NP_001155295.1 lysine-specific demethylase 4A isoform 1
NM_172382.2 NP_759014.2 lysine-specific demethylase 4A isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone H3K9 demethylase activity IDA
IDA: 通过直接分析推断
16738407 MGI
enables histone demethylase activity IDA
IDA: 通过直接分析推断
19144645 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cardiac muscle hypertrophy in response to stress IMP
IMP: 通过突变表型推断
21555854 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in pericentric heterochromatin IDA
IDA: 通过直接分析推断
16738407 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lysine-specific demethylase 4A

[histone H3]-trimethyl-L-lysine(36) demethylase 4A

[histone H3]-trimethyl-L-lysine(9) demethylase 4A

jmjC domain-containing histone demethylation protein 3A

jumonji domain containing 2A

jumonji domain-containing protein 2A

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-104048 QC6352 Inhibitor 99.13% 否
HY-100760 Toxoflavin Inhibitor 99.88% 否
HY-107573 KDM2/7-IN-1 Inhibitor 99.9% 否
HY-148807 Zavondemstat 99.29% 否
HY-110154 NSC636819 98.90% 否
HY-128343 KDM4-IN-2 Inhibitor 98.29% 否
HY-120766 NCDM-32B Inhibitor 97.0% 否
HY-RS07213 KDM4A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-100760S Toxoflavin-13C4 Inhibitor / 否
HY-150619 KDM4-IN-4 Inhibitor / 否
HY-173135 PROTAC KDM4 degrader-1 / 否
HY-RS17467 Kdm4a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23925 Kdm4a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kdm4a NCBI NCBI:9682
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