1. Gene
  2. CLUH - clustered mitochondria homolog Gene

CLUH - clustered mitochondria homolog Gene

中文名称:成簇线粒体同系物

种属: Homo sapiens

同用名: CLU1

基因 ID: 23277 | 基因类型: protein coding

关于 CLUH

Cytogenetic location: 17p13.3 Genomic coordinates (GRCh38): 17:2,689,387-2,712,020 (from NCBI)

This gene has 15 transcripts (splice variants) and 254 orthologues. Ubiquitous expression in kidney (RPKM 25.8), duodenum (RPKM 18.1) and 25 other tissues.

功能概要

启用 mRNA 结合活性。参与线粒体的细胞内分布。位于细胞质中。 [由基因组资源联盟提供,2022 年 4 月]

Enables mRNA binding activity. Involved in intracellular distribution of mitochondria. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CLUH 基因产物(3)

mRNA Protein Name
NM_001366661.1 NP_001353590.1 clustered mitochondria protein homolog isoform 1
NM_001366662.1 NP_001353591.1 clustered mitochondria protein homolog isoform 3
NM_015229.4 NP_056044.4 clustered mitochondria protein homolog isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA binding IDA
IDA: 通过直接分析推断
25349259 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intracellular distribution of mitochondria IMP
IMP: 通过突变表型推断
25349259 GOA
involved in mitochondrion organization IMP
IMP: 通过突变表型推断
25349259 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
25349259 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CLUH 蛋白结构

CLU_N

CLU_N: Mitochondrial function, CLU-N-term (64 - 139)

CLU

CLU: Clustered mitochondria (356 - 577)

eIF3_p135

eIF3_p135: Translation initiation factor eIF3 subunit 135 (764 - 949)

TPR_10

TPR_10: Tetratricopeptide repeat (1019 - 1060)

TPR_12

TPR_12: Tetratricopeptide repeat (1100 - 1177)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1309 a.a.
蛋白主名 其他名称

clustered mitochondria protein homolog

clustered mitochondria (cluA/CLU1) homolog

关联疾病

疾病名称 别名
Fish Allergy

Allergy To Fish

Dyschromatosis Universalis Hereditaria

Duh

Atrophic Rhinitis

Rhinitis, Atrophic

Ozena

Rhinitis Sicca

Dry Rhinitis

Ozaena

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus CLUH VGNC VGNC:60988
Rattus norvegicus CLUH RGD RGD:1307222
Bos taurus CLUH VGNC VGNC:50138
Canis familiaris CLUH VGNC VGNC:54935
Macaca mulatta CLUH VGNC VGNC:71370
Mus musculus CLUH MGD MGI:1921398