2. Gene
  3. Ffar1 - free fatty acid receptor 1 Gene

Ffar1 - free fatty acid receptor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gpr40

基因 ID: 233081 | 基因类型: protein coding

关于 Ffar1

功能概要

Enables bioactive lipid receptor activity. Involved in glucose homeostasis; positive regulation of transport; and response to fatty acid. Acts upstream of or within Insulin secretion. Located in plasma membrane. Is expressed in gut and male reproductive gland or organ. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FFAR1 (Free Fatty Acid Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ffar1 基因产物(1)

mRNA Protein Name
NM_194057.3 NP_918946.2 free fatty acid receptor 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor activity IDA
IDA: 通过直接分析推断
31664108 MGI
enables bioactive lipid receptor activity IDA
IDA: 通过直接分析推断
24130766 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within glucose homeostasis IMP
IMP: 通过突变表型推断
17395749 MGI
involved in glucose homeostasis IMP
IMP: 通过突变表型推断
24130766 MGI
acts upstream of or within insulin secretion IMP
IMP: 通过突变表型推断
17395749 MGI
involved in ion channel modulating, G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
31664108 MGI
involved in ligand-gated ion channel signaling pathway IDA
IDA: 通过直接分析推断
31664108 MGI
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
31664108 MGI
involved in positive regulation of calcium ion transport IDA
IDA: 通过直接分析推断
24130766 MGI
involved in positive regulation of insulin secretion IDA
IDA: 通过直接分析推断
31664108 MGI
involved in positive regulation of insulin secretion IMP
IMP: 通过突变表型推断
24130766 MGI
involved in response to fatty acid IDA
IDA: 通过直接分析推断
24130766 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
24130766 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

free fatty acid receptor 1

G protein-coupled receptor 40

G protein-coupled receptor GPR40

相关产品

Pre-clinical Phase
生物活性分子 (14)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101906 DC260126 99.57% 否
HY-W040127 Peonidin 3-O-glucoside chloride 98.02% 否
HY-W009081 Tricosanoic acid Agonist 99.96% 否
HY-147351 GPR40 agonist 6 Agonist 98.81% 否
HY-111763 GPR40/FFAR1 modulator 1 Agonist 98.28% 否
HY-148418 TUG-499 Agonist 99.78% 否
HY-148235 TP-051 Agonist / 否
HY-148247 BI-2081 Agonist / 否
HY-164870 FFAR1/FFAR4 agonist-1 Agonist / 否
HY-178395S Tricosanoic acid-d45 / 否
HY-RS04874 FFAR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W746542 Tricosanoic acid-d3 / 否
HY-RS16972 Ffar1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23415 Ffar1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ffar1 NCBI NCBI:2864
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