2. Gene
  3. Lrrk1 - leucine-rich repeat kinase 1 Gene

Lrrk1 - leucine-rich repeat kinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: mKIAA1790; C230002E15Rik; D130026O16Rik

基因 ID: 233328 | 基因类型: protein coding

关于 Lrrk1

功能概要

Predicted to enable identical protein binding activity and protein kinase activity. Acts upstream of or within several processes, including bone resorption; osteoclast development; and regulation of peptidyl-tyrosine phosphorylation. Predicted to be located in cytosol and mitochondrion. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Used to study osteopetrosis. Orthologous to human LRRK1 (leucine rich repeat kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Lrrk1 基因产物(1)

mRNA Protein Name
NM_146191.3 NP_666303.3 leucine-rich repeat serine/threonine-protein kinase 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23526378 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within bone resorption IMP
IMP: 通过突变表型推断
23526378 MGI
acts upstream of intracellular signal transduction IGI
IGI: 通过遗传相互作用推断
23526378 MGI
acts upstream of or within negative regulation of peptidyl-tyrosine phosphorylation IMP
IMP: 通过突变表型推断
23526378 MGI
acts upstream of or within osteoclast development IGI
IGI: 通过遗传相互作用推断
23526378 MGI
acts upstream of or within osteoclast development IMP
IMP: 通过突变表型推断
23526378 MGI
acts upstream of peptidyl-tyrosine phosphorylation IMP
IMP: 通过突变表型推断
23526378 MGI
acts upstream of or within positive regulation of intracellular signal transduction IGI
IGI: 通过遗传相互作用推断
23526378 MGI
acts upstream of or within positive regulation of peptidyl-tyrosine phosphorylation IMP
IMP: 通过突变表型推断
23526378 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

leucine-rich repeat serine/threonine-protein kinase 1

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-W107722 IN04 98.51% 否
HY-174420 RN277 Inhibitor / 否
HY-RS07832 LRRK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20443 Lrrk1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26952 Lrrk1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lrrk1 NCBI NCBI:79705
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z