2. Gene
  3. Palb2 - partner and localizer of BRCA2 Gene

Palb2 - partner and localizer of BRCA2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 233826 | 基因类型: protein coding

关于 Palb2

功能概要

Predicted to enable DNA binding activity. Acts upstream of or within several processes, including animal organ development; chordate embryonic development; and post-anal tail morphogenesis. Predicted to be located in nucleus. Predicted to be part of protein-containing complex. Predicted to be active in nucleoplasm. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group N; breast cancer; and pancreatic Cancer. Orthologous to human PALB2 (partner and localizer of BRCA2). [provided by Alliance of Genome Resources, Apr 2022]

Palb2 基因产物(5)

mRNA Protein Name
NM_001081238.2 NP_001074707.1 partner and localizer of BRCA2 isoform 1
NM_001289842.1 NP_001276771.1 partner and localizer of BRCA2 isoform 2
NM_001289843.1 NP_001276772.1 partner and localizer of BRCA2 isoform 3
NM_001289844.1 NP_001276773.1 partner and localizer of BRCA2 isoform 4
NM_001289845.1 NP_001276774.1 partner and localizer of BRCA2 isoform 5
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within animal organ morphogenesis IMP
IMP: 通过突变表型推断
20484223 MGI
acts upstream of apoptotic process IMP
IMP: 通过突变表型推断
21404276 MGI
acts upstream of or within embryonic organ development IMP
IMP: 通过突变表型推断
23657012 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
23657012 MGI
acts upstream of or within inner cell mass cell proliferation IMP
IMP: 通过突变表型推断
20484223 MGI
acts upstream of or within mesoderm development IMP
IMP: 通过突变表型推断
20484223 MGI
acts upstream of or within multicellular organism growth IMP
IMP: 通过突变表型推断
23657012 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
21404276 MGI
acts upstream of or within post-anal tail morphogenesis IMP
IMP: 通过突变表型推断
20484223 MGI
acts upstream of or within somitogenesis IMP
IMP: 通过突变表型推断
20484223 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

partner and localizer of BRCA2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10002 PALB2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19226 Palb2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25715 Palb2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Palb2 NCBI NCBI:79728
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