1. Gene
  2. PSD4 - pleckstrin and Sec7 domain containing 4 Gene

PSD4 - pleckstrin and Sec7 domain containing 4 Gene

中文名称:含 pleckstrin 和 Sec7 结构域 4

种属: Homo sapiens

同用名: TIC; EFA6B

基因 ID: 23550 | 基因类型: protein coding

关于 PSD4

Cytogenetic location: 2q14.1 Genomic coordinates (GRCh38): 2:113,173,971-113,209,391 (from NCBI)

This gene has 12 transcripts (splice variants), 129 orthologues and 15 paralogues. Ubiquitous expression in lymph node (RPKM 21.5), spleen (RPKM 20.1) and 22 other tissues.

功能概要

预计可启用胍基核苷酸交换因子活性和磷脂结合活性。预计参与调节 ARF 蛋白信号转导和调节催化活性。位于荷叶边膜中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable guanyl-nucleotide exchange factor activity and phospholipid binding activity. Predicted to be involved in regulation of ARF protein signal transduction and regulation of catalytic activity. Located in ruffle membrane. [provided by Alliance of Genome Resources, Apr 2022]

PSD4 基因产物(1)

mRNA Protein Name
NM_012455.3 NP_036587.2 PH and SEC7 domain-containing protein 4
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25910212 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
NOT located in cleavage furrow IDA
IDA: 通过直接分析推断
23603394 GOA
located in ruffle membrane IDA
IDA: 通过直接分析推断
23603394 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PSD4 蛋白结构

Sec7

Sec7: Sec7 domain (584 - 737)

PH_9

PH_9: Pleckstrin homology domain (778 - 892)

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  • 1056 a.a.
蛋白主名 其他名称

PH and SEC7 domain-containing protein 4

ADP-ribosylation factor guanine nucleotide-exchange factor 6

直系同源

种属 基因名 来源 基因 ID
Bos taurus PSD4 VGNC VGNC:33433
Rattus norvegicus PSD4 RGD RGD:1310289
Felis catus PSD4 VGNC VGNC:64410
Mus musculus PSD4 MGD MGI:2674093
Canis familiaris PSD4 VGNC VGNC:45084
Macaca mulatta PSD4 VGNC VGNC:76287