2. Gene
  3. Atad5 - ATPase family, AAA domain containing 5 Gene

Atad5 - ATPase family, AAA domain containing 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gm17; FRAG1; C130052G03Rik

基因 ID: 237877 | 基因类型: protein coding

关于 Atad5

功能概要

Predicted to enable DNA binding activity and DNA clamp unloader activity. Involved in cell population proliferation; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and nuclear DNA replication. Acts upstream of or within several processes, including intracellular signal transduction; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and positive regulation of B cell activation. Located in nucleus. Is expressed in liver; metanephros; midbrain ventricular layer; renal cortex; and telencephalon ventricular layer. Orthologous to human ATAD5 (ATPase family AAA domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]

Atad5 基因产物(2)

mRNA Protein Name
NM_001029856.2 NP_001025027.1 ATPase family AAA domain-containing protein 5
NM_001029856.2 NP_001025027.1 ATPase family AAA domain-containing protein 5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15983387 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within DNA damage response IMP
IMP: 通过突变表型推断
15983387 MGI
involved in cell population proliferation IMP
IMP: 通过突变表型推断
25404367 MGI
acts upstream of or within immunoglobulin production IMP
IMP: 通过突变表型推断
25404367 MGI
acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage IGI
IGI: 通过遗传相互作用推断
15983387 MGI
acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IGI
IGI: 通过遗传相互作用推断
15983387 MGI
acts upstream of isotype switching IMP
IMP: 通过突变表型推断
25404367 MGI
acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage IMP
IMP: 通过突变表型推断
15983387 MGI
involved in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
IMP: 通过突变表型推断
15983387 MGI
involved in nuclear DNA replication IMP
IMP: 通过突变表型推断
25404367 MGI
acts upstream of nucleic acid metabolic process IMP
IMP: 通过突变表型推断
25404367 MGI
acts upstream of or within positive regulation of B cell proliferation IMP
IMP: 通过突变表型推断
25404367 MGI
acts upstream of or within positive regulation of isotype switching to IgG isotypes IMP
IMP: 通过突变表型推断
25404367 MGI
acts upstream of or within regulation of mitotic cell cycle phase transition IMP
IMP: 通过突变表型推断
25404367 MGI
acts upstream of or within signal transduction in response to DNA damage IMP
IMP: 通过突变表型推断
15983387 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
15983387 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ATPase family AAA domain-containing protein 5

chromosome fragility associated gene 1

chromosome fragility-associated gene 1 protein

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-122198 ML367 Inhibitor 99.84% 否
HY-P10326 Z-ATAD-FMK Inhibitor / 否
HY-RS01123 ATAD5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18987 Atad5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25476 Atad5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atad5 NCBI NCBI:79915
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