1. Gene
  2. Adam23 - a disintegrin and metallopeptidase domain 23 Gene

Adam23 - a disintegrin and metallopeptidase domain 23 Gene

种属: Mus musculus

同用名: MDC3

基因 ID: 23792 | 基因类型: protein coding

关于 Adam23

功能概要

This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an inactive metalloprotease and disintegrin domains. Transgenic disruption of this gene in mice results in postnatal neurological defects including tremor and ataxia resulting in death by 2 weeks of age. [provided by RefSeq, Sep 2015]

Adam23 基因产物(1)

mRNA Protein Name
NM_011780.3 NP_035910.1 disintegrin and metalloproteinase domain-containing protein 23 preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16990550 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
20133599 MGI
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
20133599 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

disintegrin and metalloproteinase domain-containing protein 23

a disintegrin and metalloprotease domain 23

metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adam23 NCBI NCBI:8745