2. Gene
  3. Med24 - mediator complex subunit 24 Gene

Med24 - mediator complex subunit 24 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gse2; 911GSE; Pparb2; Thrap4; DRIP100; Pparbp2; Trap100; D11Ertd307e

基因 ID: 23989 | 基因类型: protein coding

关于 Med24

功能概要

This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene may form a submodule of the mediator complex that magnifies the effects of activators on the general transcription machinery. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

Med24 基因产物(6)

mRNA Protein Name
NM_001361993.2 NP_001348922.1 mediator of RNA polymerase II transcription subunit 24 isoform 1
NM_001361994.2 NP_001348923.1 mediator of RNA polymerase II transcription subunit 24 isoform 1
NM_001361995.2 NP_001348924.1 mediator of RNA polymerase II transcription subunit 24 isoform 2
NM_001378926.1 NP_001365855.1 mediator of RNA polymerase II transcription subunit 24 isoform 1
NM_001378927.1 NP_001365856.1 mediator of RNA polymerase II transcription subunit 24 isoform 2
NM_011869.3 NP_035999.2 mediator of RNA polymerase II transcription subunit 24 isoform 2
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within somatic stem cell population maintenance IMP
IMP: 通过突变表型推断
20720539 MGI
acts upstream of or within transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
12093747 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of mediator complex IDA
IDA: 通过直接分析推断
12093747 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mediator of RNA polymerase II transcription subunit 24

genetic suppressor element 2

mTRAP100

peroxisome proliferation activation receptor binding protein 2

thyroid hormone receptor associated protein 4

thyroid hormone receptor-associated protein 100 kDa

thyroid hormone receptor-associated protein complex

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16294 Med24 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08293 MED22 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08295 MED24 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Med24 NCBI NCBI:9862
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