1. Gene
  2. Cp - ceruloplasmin Gene

Cp - ceruloplasmin Gene

种属: Rattus norvegicus

同用名: CERP

基因 ID: 24268 | 基因类型: protein coding

关于 Cp

功能概要

Enables copper ion binding activity. Involved in several processes, including female pregnancy; gland development; and response to copper ion. Located in extracellular space. Is anchored component of plasma membrane. Used to study brain edema and iron metabolism disease. Biomarker of Wilson disease; brain ischemia; heart disease; and hyperthyroidism. Human ortholog(s) of this gene implicated in aceruloplasminemia; epilepsy; and hemosiderosis. Orthologous to human CP (ceruloplasmin). [provided by Alliance of Genome Resources, Apr 2022]

Cp 基因产物(2)

mRNA Protein Name
NM_001270961.1 NP_001257890.1 ceruloplasmin isoform 2 precursor
NM_012532.2 NP_036664.2 ceruloplasmin isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables copper ion binding IDA
IDA: 通过直接分析推断
12099680 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in female pregnancy IEP
IEP: 通过表达模式推断
28089327 RGD
involved in lactation IEP
IEP: 通过表达模式推断
28089327 RGD
involved in liver development IEP
IEP: 通过表达模式推断
2332446 RGD
involved in lung development IEP
IEP: 通过表达模式推断
2332446 RGD
involved in mammary gland involution IEP
IEP: 通过表达模式推断
28089327 RGD
involved in response to copper ion IDA
IDA: 通过直接分析推断
19700037 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
16597684 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
10660599 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
10660599 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ceruloplasmin

bilitranslocase

ceruloplasmin (ferroxidase)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cp NCBI NCBI:1356
Canis familiaris Cp NCBI NCBI:442963
Macaca fascicularis Cp NCBI
Mus musculus Cp NCBI NCBI:12870
Susscrofa domestica Cp NCBI
Macaca mulatta Cp NCBI NCBI:712210