2. Gene
  3. Gh1 - growth hormone 1 Gene

Gh1 - growth hormone 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Gh; Ghb1; RNGHGP

基因 ID: 24391 | 基因类型: protein coding

关于 Gh1

功能概要

Enables hormone activity. Involved in several processes, including cellular response to alkaline pH; cellular response to thyroid hormone stimulus; and generation of neurons. Located in several cellular components, including collagen-containing extracellular matrix; mitochondrion; and secretory granule. Used to study isolated growth hormone deficiency and type 1 diabetes mellitus. Biomarker of congenital hypothyroidism; osteoporosis; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); autoimmune disease of endocrine system (multiple); diabetic retinopathy; isolated growth hormone deficiency (multiple); and progeria. Orthologous to several human genes including GH1 (growth hormone 1). [provided by Alliance of Genome Resources, Apr 2022]

Gh1 基因产物(1)

mRNA Protein Name
NM_001034848.2 NP_001030020.2 somatotropin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hormone activity IDA
IDA: 通过直接分析推断
17258692 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to alkaline pH IEP
IEP: 通过表达模式推断
23639351 RGD
involved in cellular response to thyroid hormone stimulus IEP
IEP: 通过表达模式推断
1730572 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
18208550 RGD
involved in lung alveolus development IMP
IMP: 通过突变表型推断
18985281 RGD
involved in neuroblast proliferation IDA
IDA: 通过直接分析推断
19524466 RGD
involved in positive regulation of growth IMP
IMP: 通过突变表型推断
8398130 RGD
involved in positive regulation of neurogenesis IDA
IDA: 通过直接分析推断
19524466 RGD
involved in positive regulation of steroid hormone biosynthetic process IDA
IDA: 通过直接分析推断
17023532 RGD
involved in regulation of response to nutrient levels IDA
IDA: 通过直接分析推断
17258692 RGD
involved in response to cytokine IEP
IEP: 通过表达模式推断
18753332 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
9681512 RGD
involved in response to light stimulus IDA
IDA: 通过直接分析推断
19091612 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
19439817 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
9255605 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
19382144 RGD
located in secretory granule IDA
IDA: 通过直接分析推断
2980232 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

somatotropin

growth hormone b1

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-D1515 FM1-84 98.92% 否
HY-W011410 4-Nitrophenyl β-D-mannopyranoside Substrate 98.50% 否
HY-P3056 GHRF, ovine / 否
HY-RS05408 GH1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS05580 Gnrhr Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24406 Gh1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gh1 NCBI NCBI:2688
Mus musculus Gh1 NCBI
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