1. Gene
  2. HPRT1 - Hprt1 hypoxanthine phosphoribosyltransferase 1 Gene

HPRT1 - Hprt1 hypoxanthine phosphoribosyltransferase 1 Gene

种属: Rattus norvegicus

同用名: Hprt; Hgprtase

基因 ID: 24465 | 基因类型: protein coding

关于 HPRT1

功能概要

Enables hypoxanthine phosphoribosyltransferase activity. Involved in several processes, including cellular response to Insulin stimulus; hypoxanthine metabolic process; and spermatogenesis. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in HRPT-related hyperuricemia and Lesch-Nyhan syndrome. Orthologous to human HPRT1 (hypoxanthine phosphoribosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

HPRT1 基因产物(1)

mRNA Protein Name
NM_012583.2 NP_036715.1 hypoxanthine-guanine phosphoribosyltransferase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hypoxanthine phosphoribosyltransferase activity IDA
IDA: 通过直接分析推断
6206848 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
2185659 RGD
involved in hypoxanthine metabolic process IDA
IDA: 通过直接分析推断
6206848 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
12193390 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

hypoxanthine-guanine phosphoribosyltransferase

HGPRT

hypoxanthine guanine phosphoribosyl transferase 1

hypoxanthine phosphoribosyl transferase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens HPRT1 NCBI NCBI:3251