2. Gene
  3. Vamp2 - vesicle-associated membrane protein 2 Gene

Vamp2 - vesicle-associated membrane protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: SYB; Syb2; RATVAMPB; RATVAMPIR

基因 ID: 24803 | 基因类型: protein coding

关于 Vamp2

功能概要

Enables several functions, including protein C-terminus binding activity; syntaxin-1 binding activity; and transmembrane transporter binding activity. Involved in several processes, including SNARE complex assembly; exocytosis; and regulation of delayed rectifier Potassium Channel activity. Located in neuron projection terminus; plasma membrane; and secretory vesicle. Part of synaptobrevin 2-SNAP-25-syntaxin-1a complex; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex; and synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex. Is integral component of synaptic vesicle membrane. Orthologous to human VAMP2 (vesicle associated membrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Vamp2 基因产物(1)

mRNA Protein Name
NM_012663.2 NP_036795.1 vesicle-associated membrane protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SNARE binding IDA
IDA: 通过直接分析推断
7553862 RGD
enables SNARE binding IPI
IPI: 通过物理相互作用推断
9671503 RGD
enables calcium-dependent protein binding IPI
IPI: 通过物理相互作用推断
12526776 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
21856303 RGD
enables lipid binding EXP
EXP: 通过实验结果推断
19918058 RGD
enables molecular adaptor activity EXP
EXP: 通过实验结果推断
19918058 RGD
enables myosin binding IPI
IPI: 通过物理相互作用推断
16030255 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
8567678 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
8567678 RGD
enables syntaxin-1 binding IDA
IDA: 通过直接分析推断
7553862 RGD
enables syntaxin-1 binding IPI
IPI: 通过物理相互作用推断
16030255 RGD
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
19077057 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in SNARE complex assembly IMP
IMP: 通过突变表型推断
9671503 RGD
involved in protein-containing complex assembly IDA
IDA: 通过直接分析推断
10051443 RGD
involved in regulation of delayed rectifier potassium channel activity IDA
IDA: 通过直接分析推断
19690160 RGD
involved in regulation of exocytosis IMP
IMP: 通过突变表型推断
11245593 RGD
involved in regulation of synaptic vesicle recycling IMP
IMP: 通过突变表型推断
21808019 RGD
involved in response to glucose IDA
IDA: 通过直接分析推断
15537656 RGD
involved in synaptic vesicle exocytosis IDA
IDA: 通过直接分析推断
1331807 RGD
involved in synaptic vesicle exocytosis IEP
IEP: 通过表达模式推断
1331807 RGD
involved in synaptic vesicle exocytosis IMP
IMP: 通过突变表型推断
1331807 RGD
involved in vesicle-mediated transport IMP
IMP: 通过突变表型推断
11245593 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SNARE complex IDA
IDA: 通过直接分析推断
10051443 RGD
located in neuron projection terminus IDA
IDA: 通过直接分析推断
10908612 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
15537656 RGD
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
26488171 RGD
is active in postsynaptic density IDA
IDA: 通过直接分析推断
26488171 RGD
located in secretory granule IDA
IDA: 通过直接分析推断
15537656 RGD
located in synaptic vesicle IDA
IDA: 通过直接分析推断
10908612 RGD
is active in synaptic vesicle membrane EXP
EXP: 通过实验结果推断
17110340 RGD
is active in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
17110340 RGD
located in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
23792689 RGD
part of synaptobrevin 2-SNAP-25-syntaxin-1a complex IDA
IDA: 通过直接分析推断
7553862 RGD
part of synaptobrevin 2-SNAP-25-syntaxin-1a complex IMP
IMP: 通过突变表型推断
9671503 RGD
part of synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex IDA
IDA: 通过直接分析推断
7553862 RGD
part of synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex IDA
IDA: 通过直接分析推断
19132534 RGD
part of voltage-gated potassium channel complex IDA
IDA: 通过直接分析推断
19077057 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

vesicle-associated membrane protein 2

Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2)

VAMP-2

Vesicle-associated membrane protein (synaptobrevin 2)

synaptobrevin-2

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P10809 VAMP Inhibitor 98.13% Phase 2
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P5366 PEP1 Modulator 99.16% 否
HY-RS15594 VAMP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21080 Vamp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27597 Vamp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vamp2 NCBI NCBI:6844
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