2. Gene
  3. Glul - glutamate-ammonia ligase Gene

Glul - glutamate-ammonia ligase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Glns

基因 ID: 24957 | 基因类型: protein coding

关于 Glul

功能概要

Enables several functions, including anion binding activity; dynein light chain binding activity; and metal ion binding activity. Involved in glutamine metabolic process; positive regulation of cell communication; and positive regulation of epithelial cell proliferation. Located in several cellular components, including myelin sheath; perikaryon; and rough endoplasmic reticulum. Part of protein-containing complex. Used to study obesity; temporal lobe epilepsy; and visual epilepsy. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; and temporal lobe epilepsy. Orthologous to human GLUL (glutamate-ammonia Ligase). [provided by Alliance of Genome Resources, Apr 2022]

Glul 基因产物(2)

mRNA Protein Name
NM_001393804.1 NP_001380733.1 glutamine synthetase
NM_017073.4 NP_058769.4 glutamine synthetase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
28323 RGD
enables dynein light chain binding IPI
IPI: 通过物理相互作用推断
14760703 RGD
enables glutamate binding IDA
IDA: 通过直接分析推断
28323 RGD
enables glutamine synthetase activity IDA
IDA: 通过直接分析推断
28323 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
28323 RGD
enables magnesium ion binding IDA
IDA: 通过直接分析推断
28323 RGD
enables manganese ion binding IDA
IDA: 通过直接分析推断
28323 RGD
enables nickel cation binding IDA
IDA: 通过直接分析推断
21254280 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ammonia assimilation cycle IDA
IDA: 通过直接分析推断
28323 RGD
involved in glutamate metabolic process IDA
IDA: 通过直接分析推断
4403443 RGD
involved in glutamine biosynthetic process IDA
IDA: 通过直接分析推断
28323 RGD
involved in positive regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
9915876 RGD
involved in positive regulation of insulin secretion IMP
IMP: 通过突变表型推断
12575909 RGD
involved in positive regulation of synaptic transmission, glutamatergic IMP
IMP: 通过突变表型推断
10696145 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
NOT located in axon terminus IDA
IDA: 通过直接分析推断
31966 RGD
located in axon terminus IDA
IDA: 通过直接分析推断
6105901 RGD
located in cell projection IDA
IDA: 通过直接分析推断
31966 RGD
located in myelin sheath IDA
IDA: 通过直接分析推断
17960831 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
31966 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
28323 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

glutamine synthetase

GS

Glutamine synthetase (glutamate-ammonia ligase)

glutamate decarboxylase

glutamate-ammonia ligase (glutamine synthase)

glutamate-ammonia ligase (glutamine synthetase)

glutamine synthetase 1

palmitoyltransferase GLUL

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05509 GLUL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17491 Glul Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23948 Glul Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Glul NCBI NCBI:2752
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