2. Gene
  3. GNMT - Gnmt glycine N-methyltransferase Gene

GNMT - Gnmt glycine N-methyltransferase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 25134 | 基因类型: protein coding

关于 GNMT

功能概要

Enables several functions, including S-adenosyl-L-methionine binding activity; carboxylic acid binding activity; and glycine N-methyltransferase activity. Involved in several processes, including S-adenosylmethionine metabolic process; alpha-amino acid metabolic process; and protein homotetramerization. Located in cytosol and nucleus. Part of methyltransferase complex. Human ortholog(s) of this gene implicated in glycine N-methyltransferase deficiency. Orthologous to human GNMT (glycine N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

GNMT 基因产物(1)

mRNA Protein Name
NM_017084.1 NP_058780.1 glycine N-methyltransferase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables S-adenosyl-L-methionine binding IMP
IMP: 通过突变表型推断
10756111 RGD
enables S-adenosylmethionine-dependent methyltransferase activity IDA
IDA: 通过直接分析推断
15347642 RGD
enables folic acid binding IDA
IDA: 通过直接分析推断
17158459 RGD
enables glycine N-methyltransferase activity IDA
IDA: 通过直接分析推断
12054489 RGD
enables glycine N-methyltransferase activity IMP
IMP: 通过突变表型推断
10756111 RGD
enables glycine binding IDA
IDA: 通过直接分析推断
15340920 RGD
enables glycine binding IMP
IMP: 通过突变表型推断
10756111 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
10756111 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in S-adenosylhomocysteine metabolic process IDA
IDA: 通过直接分析推断
15347642 RGD
involved in S-adenosylhomocysteine metabolic process IMP
IMP: 通过突变表型推断
10756111 RGD
involved in S-adenosylmethionine metabolic process IDA
IDA: 通过直接分析推断
15340920 RGD
involved in S-adenosylmethionine metabolic process IMP
IMP: 通过突变表型推断
10756111 RGD
involved in glycine metabolic process IMP
IMP: 通过突变表型推断
10756111 RGD
involved in methylation IMP
IMP: 通过突变表型推断
10756111 RGD
involved in protein homotetramerization IPI
IPI: 通过物理相互作用推断
15340920 RGD
involved in sarcosine metabolic process IMP
IMP: 通过突变表型推断
18501206 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
6587377 RGD
part of methyltransferase complex IMP
IMP: 通过突变表型推断
10756111 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

glycine N-methyltransferase

folate-binding protein

glycine methyltransferase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05569 GNMT Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17639 Gnmt Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24099 Gnmt Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens GNMT NCBI NCBI:27232
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