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  2. Lipe - lipase E, hormone sensitive type Gene

Lipe - lipase E, hormone sensitive type Gene

种属: Rattus norvegicus

同用名: HSL; REH

基因 ID: 25330 | 基因类型: protein coding

关于 Lipe

功能概要

Enables carboxylic ester hydrolase activity. Involved in female pregnancy; response to xenobiotic stimulus; and triglyceride catabolic process. Located in cytoplasm and extracellular space. Used to study arteriosclerosis and heart disease. Biomarker of obesity. Human ortholog(s) of this gene implicated in familial partial lipodystrophy type 6 and hypertension. Orthologous to human LIPE (Lipase E, hormone sensitive type). [provided by Alliance of Genome Resources, Apr 2022]

Lipe 基因产物(1)

mRNA Protein Name
NM_012859.1 NP_036991.1 hormone-sensitive lipase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables diacylglycerol lipase activity IDA
IDA: 通过直接分析推断
6643478 RGD
enables hydrolase activity, acting on ester bonds IDA
IDA: 通过直接分析推断
15697220 RGD
enables monoacylglycerol lipase activity IDA
IDA: 通过直接分析推断
15627655 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10318917 RGD
enables retinyl-palmitate esterase activity IDA
IDA: 通过直接分析推断
9162045 RGD
enables sterol ester esterase activity IDA
IDA: 通过直接分析推断
9162045 RGD
enables triacylglycerol lipase activity IDA
IDA: 通过直接分析推断
9162045 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in female pregnancy IEP
IEP: 通过表达模式推断
16328496 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11016888 RGD
involved in triglyceride catabolic process IDA
IDA: 通过直接分析推断
14739077 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
15654127 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

hormone-sensitive lipase

lipase, hormone sensitive

monoacylglycerol lipase LIPE

retinyl ester hydrolase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lipe NCBI NCBI:3991