IFI6 - interferon alpha inducible protein 6 Gene

中文名称：干扰素α诱导蛋白 6

种属: Homo sapiens

同用名: 6-16; G1P3; FAM14C; IFI616; IFI-6-16

关于 IFI6

功能概要

该基因最初被鉴定为干扰素诱导的众多基因之一。编码的蛋白质可能在细胞凋亡的调节中起关键作用。一个由类似于哺乳动物剪接供体共有序列的 12 个核苷酸重复元素的 26 个重复组成的小卫星在第二个外显子末端附近开始。已经描述了通过使用两个下游重复单元作为剪接供体位点来编码不同亚型的选择性剪接转录变体。[RefSeq 提供，2008 年 7 月]

This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of Apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described. [provided by RefSeq, Jul 2008]