1. Gene
  2. Ahsg - alpha-2-HS-glycoprotein Gene

Ahsg - alpha-2-HS-glycoprotein Gene

种属: Rattus norvegicus

同用名: pp63; Aa2-066

基因 ID: 25373 | 基因类型: protein coding

关于 Ahsg

功能概要

Enables receptor signaling protein tyrosine kinase inhibitor activity. Involved in several processes, including animal organ development; negative regulation of bone mineralization; and positive regulation of bone resorption. Located in collagen-containing extracellular matrix and extracellular space. Part of protein-containing complex. Human ortholog(s) of this gene implicated in alopecia-mental retardation syndrome 1; coronary artery disease; and type 2 diabetes mellitus. Orthologous to human AHSG (alpha 2-HS glycoprotein). [provided by Alliance of Genome Resources, Apr 2022]

Ahsg 基因产物(1)

mRNA Protein Name
NM_012898.5 NP_037030.2 alpha-2-HS-glycoprotein precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables receptor signaling protein tyrosine kinase inhibitor activity IDA
IDA: 通过直接分析推断
2766355 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
1659407 RGD
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
7513166 RGD
involved in cerebral cortex development IEP
IEP: 通过表达模式推断
2423927 RGD
involved in male gonad development IMP
IMP: 通过突变表型推断
6530227 RGD
involved in negative regulation of bone mineralization IMP
IMP: 通过突变表型推断
8702833 RGD
involved in negative regulation of cell growth IDA
IDA: 通过直接分析推断
2766355 RGD
involved in negative regulation of insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
2766355 RGD
involved in positive regulation of bone resorption IMP
IMP: 通过突变表型推断
10500999 RGD
involved in protein-containing complex assembly IPI
IPI: 通过物理相互作用推断
12676928 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
7794128 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
11239198 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
12676928 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

alpha-2-HS-glycoprotein

59 kDa bone sialic acid-containing protein

BSP

alpha 2 HS-glycoprotein alpha 2 (fetuin)

fetuin-A

glycoprotein PP63

phosphorylated N-glycoprotein pp63

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ahsg NCBI NCBI:197
Mus musculus Ahsg NCBI NCBI:11625