2. Gene
  3. Hbegf - heparin-binding EGF-like growth factor Gene

Hbegf - heparin-binding EGF-like growth factor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Dtr; GFHB; Hegfl; Hb-egf

基因 ID: 25433 | 基因类型: protein coding

关于 Hbegf

功能概要

Enables epidermal growth factor receptor binding activity and growth factor activity. Involved in epidermal growth factor receptor signaling pathway; negative regulation of elastin biosynthetic process; and positive regulation of cell growth. Predicted to be located in cell surface. Predicted to be active in extracellular space. Predicted to be integral component of plasma membrane. Biomarker of acute kidney failure. Human ortholog(s) of this gene implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. Orthologous to human HBEGF (heparin binding EGF like growth factor). [provided by Alliance of Genome Resources, Apr 2022]

Hbegf 基因产物(1)

mRNA Protein Name
NM_012945.2 NP_037077.1 proheparin-binding EGF-like growth factor precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables epidermal growth factor receptor binding IMP
IMP: 通过突变表型推断
15486316 RGD
enables growth factor activity IMP
IMP: 通过突变表型推断
15486316 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epidermal growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
15486316 RGD
involved in negative regulation of elastin biosynthetic process IDA
IDA: 通过直接分析推断
12882762 RGD
involved in positive regulation of cell growth IDA
IDA: 通过直接分析推断
11956950 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

proheparin-binding EGF-like growth factor

Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor)

heparin binding epidermal growth factor-like growth factor

heparin-binding epidermal -growth - like growth factor

heparin-binding epidermal -growth factor

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-180536 HB-EGF-IN-1 Inhibitor / 否
HY-RS06029 HBEGF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174671 Human HBEGF mRNA / 否
HY-RS17058 Hbegf Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23502 Hbegf Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hbegf NCBI NCBI:1839
Mus musculus Hbegf NCBI NCBI:15200
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