2. Gene
  3. Lhcgr - luteinizing hormone/choriogonadotropin receptor Gene

Lhcgr - luteinizing hormone/choriogonadotropin receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Lhr; LSHR; LSH-R; LH/CG-R

基因 ID: 25477 | 基因类型: protein coding

关于 Lhcgr

功能概要

Enables several functions, including ATPase binding activity; identical protein binding activity; and peptide hormone binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; activation of Adenylate Cyclase activity; and arachidonic acid secretion. Located in several cellular components, including endoplasmic reticulum; endosome; and lysosome. Is integral component of plasma membrane and intrinsic component of external side of plasma membrane. Part of receptor complex. Human ortholog(s) of this gene implicated in Leydig cell hypoplasia; Leydig cell tumor; breast cancer; familial male-limited precocious puberty; and gonadal disease. Orthologous to human LHCGR (luteinizing hormone/choriogonadotropin receptor). [provided by Alliance of Genome Resources, Apr 2022]

Lhcgr 基因产物(1)

mRNA Protein Name
NM_012978.2 NP_037110.1 lutropin-choriogonadotropic hormone receptor precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATPase binding IPI
IPI: 通过物理相互作用推断
17588601 RGD
enables G protein-coupled peptide receptor activity IDA
IDA: 通过直接分析推断
2502842 RGD
enables identical protein binding IDA
IDA: 通过直接分析推断
11266505 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
2601325 RGD
enables peptide hormone binding IDA
IDA: 通过直接分析推断
15901736 RGD
enables peptide hormone binding IMP
IMP: 通过突变表型推断
1714448 RGD
enables peptide hormone binding IPI
IPI: 通过物理相互作用推断
2601325 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in activation of adenylate cyclase activity IDA
IDA: 通过直接分析推断
8440169 RGD
involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
2502842 RGD
involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
1714448 RGD
involved in arachidonate secretion IDA
IDA: 通过直接分析推断
9291830 RGD
involved in hormone-mediated signaling pathway IDA
IDA: 通过直接分析推断
2502842 RGD
involved in luteinizing hormone signaling pathway IDA
IDA: 通过直接分析推断
3030841 RGD
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
3026357 RGD
involved in positive regulation of calcium ion transport into cytosol IDA
IDA: 通过直接分析推断
8187959 RGD
involved in positive regulation of calcium-mediated signaling IDA
IDA: 通过直接分析推断
8187959 RGD
involved in positive regulation of hormone biosynthetic process IDA
IDA: 通过直接分析推断
3026357 RGD
involved in positive regulation of release of sequestered calcium ion into cytosol IDA
IDA: 通过直接分析推断
8187959 RGD
involved in protein targeting to lysosome IMP
IMP: 通过突变表型推断
10847593 RGD
involved in regulation of steroid biosynthetic process IEP
IEP: 通过表达模式推断
17241129 RGD
involved in response to luteinizing hormone IDA
IDA: 通过直接分析推断
9553128 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
9653071 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endosome IDA
IDA: 通过直接分析推断
10847593 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
2174034 RGD
part of receptor complex IDA
IDA: 通过直接分析推断
11266505 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lutropin-choriogonadotropic hormone receptor

LH receptor

LH/CG receptor

luteinizing hormone receptor

luteinizing hormone/chorionic gonadotropin receptor

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-150210 FSHR agonist 1 Agonist 99.45% 否
HY-100271 Org41841 Agonist 99.77% 否
HY-RS07624 LHCGR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P10594 Myr-Arf1(2–17) / 否
HY-RS17915 Lhcgr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24384 Lhcgr Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lhcgr NCBI NCBI:3973
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