1. Gene
  2. Ppia - peptidylprolyl isomerase A Gene

Ppia - peptidylprolyl isomerase A Gene

种属: Rattus norvegicus

同用名: CYCA; CyP-A

基因 ID: 25518 | 基因类型: protein coding

关于 Ppia

功能概要

Enables cyclosporin A binding activity. Involved in negative regulation of phosphoprotein Phosphatase activity. Predicted to be located in cytosol; extracellular region; and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Used to study epilepsy. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to human PPIA (peptidylprolyl isomerase A). [provided by Alliance of Genome Resources, Apr 2022]

Ppia 基因产物(1)

mRNA Protein Name
NM_017101.1 NP_058797.1 peptidyl-prolyl cis-trans isomerase A
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cyclosporin A binding IDA
IDA: 通过直接分析推断
19832699 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of calcineurin-mediated signaling IDA
IDA: 通过直接分析推断
19832699 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

peptidyl-prolyl cis-trans isomerase A

PPIase A

cyclophilin A

cyclosporin A-binding protein

p1B15

p31

rotamase A

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ppia NCBI NCBI:5478
Mus musculus Ppia NCBI NCBI:268373