2. Gene
  3. Gnai3 - G protein subunit alpha i3 Gene

Gnai3 - G protein subunit alpha i3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: GIP3A

基因 ID: 25643 | 基因类型: protein coding

关于 Gnai3

功能概要

Enables G protein-coupled serotonin receptor binding activity; GTPase activating protein binding activity; and protein domain specific binding activity. Involved in several processes, including positive regulation of NAD(P)H oxidase activity; positive regulation of superoxide anion generation; and positive regulation of vascular associated smooth muscle cell proliferation. Located in membrane raft; plasma membrane; and zymogen granule. Biomarker of hypertension. Orthologous to human GNAI3 (G protein subunit alpha i3). [provided by Alliance of Genome Resources, Apr 2022]

Gnai3 基因产物(1)

mRNA Protein Name
NM_013106.2 NP_037238.1 guanine nucleotide-binding protein G(i) subunit alpha-3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled serotonin receptor binding IPI
IPI: 通过物理相互作用推断
16772521 RGD
enables GTPase activating protein binding IPI
IPI: 通过物理相互作用推断
11387333 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
8524874 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
11387333 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of apoptotic signaling pathway IMP
IMP: 通过突变表型推断
25633408 RGD
involved in positive regulation of NAD(P)H oxidase activity IMP
IMP: 通过突变表型推断
27912212 RGD
involved in positive regulation of superoxide anion generation IMP
IMP: 通过突变表型推断
27912212 RGD
involved in positive regulation of vascular associated smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
27912212 RGD
involved in vesicle fusion IDA
IDA: 通过直接分析推断
12038977 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
11387333 RGD
located in zymogen granule IDA
IDA: 通过直接分析推断
12038977 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

guanine nucleotide-binding protein G(i) subunit alpha-3

Guanine nucleotide binding, protein, alpha inhibiting polypeptide 3

g(i) alpha-3

guanine nucleotide binding protein (G protein), alpha inhibiting 3

guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3

guanine nucleot

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05536 GNAI3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20413 Gnai3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26922 Gnai3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gnai3 NCBI NCBI:2773
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