Syt1 - synaptotagmin 1 Gene

种属: Rattus norvegicus

同用名: P65

基因 ID: 25716 | 基因类型: protein coding

关于 Syt1

功能概要

Enables several functions, including Calmodulin binding activity; phospholipid binding activity; and syntaxin binding activity. Involved in several processes, including positive regulation of dopamine secretion; regulation of vesicle-mediated transport; and response to calcium ion. Located in several cellular components, including excitatory synapse; neuron projection terminus; and secretory vesicle. Is active in hippocampal mossy fiber to CA3 synapse. Is integral component of synaptic vesicle membrane. Biomarker of visual epilepsy. Orthologous to human SYT1 (synaptotagmin 1). [provided by Alliance of Genome Resources, Apr 2022]

Syt1 基因产物(1)

mRNA	Protein	Name
NM_001033680.2	NP_001028852.2	synaptotagmin-1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables SNARE binding	IDA IDA: 通过直接分析推断	12860971	RGD
enables SNARE binding	IPI IPI: 通过物理相互作用推断	12526776	RGD
enables calcium ion binding	IDA IDA: 通过直接分析推断	15340165	RGD
enables calcium ion binding	IMP IMP: 通过突变表型推断	22711810	RGD
enables calcium ion sensor activity	EXP EXP: 通过实验结果推断	24001110	RGD
enables calcium-dependent phospholipid binding	IDA IDA: 通过直接分析推断	7791877	RGD
enables calcium-dependent protein binding	IDA IDA: 通过直接分析推断	9830048	RGD
enables calmodulin binding	IDA IDA: 通过直接分析推断	2333096	RGD
enables clathrin binding	IDA IDA: 通过直接分析推断	7791877	RGD
enables identical protein binding	EXP EXP: 通过实验结果推断	38177243	RGD
enables identical protein binding	IPI IPI: 通过物理相互作用推断	8621455	RGD
enables molecular condensate scaffold activity	EXP EXP: 通过实验结果推断	38177243	RGD
enables molecular condensate scaffold activity	IDA IDA: 通过直接分析推断	38177243	RGD
enables phosphatidylinositol-4,5-bisphosphate binding	IDA IDA: 通过直接分析推断	12860971	RGD
enables phosphatidylserine binding	IDA IDA: 通过直接分析推断	12860971	RGD
enables phospholipid binding	IDA IDA: 通过直接分析推断	2333096	RGD
enables protein binding	IPI IPI: 通过物理相互作用推断	8567678	RGD
enables protein heterodimerization activity	IPI IPI: 通过物理相互作用推断	10397765	RGD
enables syntaxin binding	IDA IDA: 通过直接分析推断	7791877	RGD
enables syntaxin binding	IPI IPI: 通过物理相互作用推断	10397765	RGD
enables syntaxin-1 binding	IDA IDA: 通过直接分析推断	12526776	RGD
enables syntaxin-1 binding	IPI IPI: 通过物理相互作用推断	10397765	RGD
enables syntaxin-3 binding	IPI IPI: 通过物理相互作用推断	10397765	RGD

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in cellular response to calcium ion	IMP IMP: 通过突变表型推断	12526776	RGD
involved in detection of calcium ion	IDA IDA: 通过直接分析推断	22229667	RGD
involved in non-membrane-bounded organelle assembly	IDA IDA: 通过直接分析推断	38177243	RGD
involved in positive regulation of calcium ion-dependent exocytosis	IDA IDA: 通过直接分析推断	21551071	RGD
involved in positive regulation of dopamine secretion	IMP IMP: 通过突变表型推断	28370453	RGD
involved in positive regulation of vesicle fusion	IDA IDA: 通过直接分析推断	18508778	RGD
involved in protein heterooligomerization	IPI IPI: 通过物理相互作用推断	9830048	RGD
involved in regulation of calcium ion-dependent exocytosis	IMP IMP: 通过突变表型推断	11751925	RGD
involved in regulation of regulated secretory pathway	IMP IMP: 通过突变表型推断	12526776	RGD
involved in regulation of synaptic vesicle exocytosis	IDA IDA: 通过直接分析推断	28057568	RGD
involved in regulation of vesicle fusion	IMP IMP: 通过突变表型推断	24001110	RGD
involved in response to calcium ion	IDA IDA: 通过直接分析推断	18508778	RGD
involved in vesicle docking	IDA IDA: 通过直接分析推断	22229667	RGD
involved in vesicle docking	IMP IMP: 通过突变表型推断	24001110	RGD
involved in vesicle fusion	IDA IDA: 通过直接分析推断	24001110	RGD
involved in vesicle fusion	IMP IMP: 通过突变表型推断	24001110	RGD

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	10967100	RGD
located in dense core granule	IDA IDA: 通过直接分析推断	11751925	RGD
located in excitatory synapse	IDA IDA: 通过直接分析推断	19730411	RGD
is active in hippocampal mossy fiber to CA3 synapse	IDA IDA: 通过直接分析推断	7298720	RGD
located in neuron projection terminus	IDA IDA: 通过直接分析推断	10397765	RGD
located in plasma membrane	IDA IDA: 通过直接分析推断	18179895	RGD
is active in postsynaptic cytosol	IDA IDA: 通过直接分析推断	28686803	RGD
is active in postsynaptic density	IDA IDA: 通过直接分析推断	28686803	RGD
is active in postsynaptic membrane	IDA IDA: 通过直接分析推断	28686803	RGD
is active in presynaptic active zone	IDA IDA: 通过直接分析推断	28686803	RGD
is active in presynaptic cytosol	IDA IDA: 通过直接分析推断	28686803	RGD
located in secretory granule	IDA IDA: 通过直接分析推断	15015935	RGD
located in synaptic vesicle	IDA IDA: 通过直接分析推断	18179895	RGD
is active in synaptic vesicle membrane	IDA IDA: 通过直接分析推断	7298720	RGD
located in synaptic vesicle membrane	IDA IDA: 通过直接分析推断	23792689	RGD

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

synaptotagmin-1

synaptotagmin I

sytI

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-P5043	α-Synuclein (67-78) (human)		/	否
HY-RS14106	SYT1 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS22338	Syt1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS28860	Syt1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Homo sapiens	Syt1	NCBI	NCBI:6857

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
粤ICP备2021105330号-3 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2026 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

粤ICP备2021105330号-3

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

Syt1 - synaptotagmin 1 Gene

关于 Syt1

功能概要

Syt1 基因产物(1)

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

Syt1 - synaptotagmin 1 Gene

关于 Syt1

功能概要

Syt1 基因产物(1)

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z