2. Gene
  3. MXRA5 - matrix remodeling associated 5 Gene

MXRA5 - matrix remodeling associated 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品

中文名称：矩阵重塑相关 5

种属: Homo sapiens

基因 ID: 25878 | 基因类型: protein coding

关于 MXRA5

Cytogenetic location: Xp22.33 Genomic coordinates (GRCh38): X:3,308,565-3,346,652 (from NCBI)

This gene has 1 transcript (splice variant), 202 orthologues and 36 paralogues. Ubiquitous expression in skin (RPKM 16.1), urinary bladder (RPKM 11.0) and 22 other tissues.

功能概要

该基因编码一种基质重塑相关蛋白。该蛋白质包含 7 个富含亮氨酸的重复序列和 12 个与珍珠聚糖相关的免疫球蛋白样 C2 型结构域。该基因在 Y 染色体上有一个假基因。[RefSeq 提供，2010 年 3 月]

This gene encodes one of the matrix-remodelling associated proteins. This protein contains 7 leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan. This gene has a pseudogene on chromosome Y. [provided by RefSeq, Mar 2010]

MXRA5 基因产物(1)

mRNA Protein Name
NM_015419.4 NP_056234.2 matrix-remodeling-associated protein 5 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to transforming growth factor beta IMP
IMP: 通过突变表型推断
27599751 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MXRA5 蛋白结构

LRR_8

LRR_8: Leucine rich repeat (111 - 163)

I-set

I-set: Immunoglobulin I-set domain (487 - 560)

I-set

I-set: Immunoglobulin I-set domain (590 - 668)

I-set

I-set: Immunoglobulin I-set domain (1857 - 1944)

I-set

I-set: Immunoglobulin I-set domain (1956 - 2042)

I-set

I-set: Immunoglobulin I-set domain (2052 - 2139)

I-set

I-set: Immunoglobulin I-set domain (2151 - 2238)

I-set

I-set: Immunoglobulin I-set domain (2251 - 2341)

I-set

I-set: Immunoglobulin I-set domain (2355 - 2434)

I-set

I-set: Immunoglobulin I-set domain (2458 - 2535)

I-set

I-set: Immunoglobulin I-set domain (2549 - 2633)

Ig_2

Ig_2: Immunoglobulin domain (2648 - 2726)

I-set

I-set: Immunoglobulin I-set domain (2733 - 2826)

  • 0
  • 500
  • 1000
  • 1500
  • 2000
  • 2500
  • 2828 a.a.
蛋白主名 其他名称

matrix-remodeling-associated protein 5

adhesion protein with leucine-rich repeats and Immunoglobulin domains related to perlecan

关联疾病

疾病名称 别名
Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma
Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney Disease, Adult Type

Adpkd

Polycystic Kidney Diseases

Polycystic Kidney, Autosomal Dominant

Congenital Biliary Ectasias

Polycystic Kidney And Hepatic Disease 1

Polycystic Kidney Disease, Autosomal Dominant

Kidney, Polycystic, Disease, Autosomal Dominant

Adult Polycystic Kidney Disease

Polycystic Kidney, Adult Type

Apckd - [Autosomal Polycystic Kidney Disease]
Phosphoglycerate Dehydrogenase Deficiency

Phgdh Deficiency

3-Phosphoglycerate Dehydrogenase Deficiency

PHGDHD

3-Pgdh Deficiency

3-Phosphoglycerate Dehydrogenase Deficiency, Infantile/Juvenile Form

Phgdh Deficiency, Infantile/Juvenile Form

Deficiency, Phosphoglycerate Dehydrogenase
Chronic Kidney Disease

Chronic Renal Disease

Chronic Kidney Failure

Ckd

Chronic Renal Failure

Kidney Failure, Chronic

Chronic Renal Failure Syndrome

Crf

Renal Failure - Chronic

Renal Failure Chronic

Chronic Kidney Diseases

Chronic Kidney Disease Stage 5

Ckd - [Chronic Kidney Disease]

Crf - [Chronic Renal Failure]

Chronic Kidney Impairment

Chronic Renal Impairment

Chronic Kidney Shutdown

Chronic Hypoxic Kidney Failure

Chronic Kidney Collapse

Chronic Renal Insufficiency

Chronic Kidney Toxaemia

Chronic Kidney Hypofunction

Chronic Renal Suppression

Chronic Renal Failure, Stage 5

Ckd - [Chronic Kidney Disease] Stage 5

End Stage Kidney Failure

End Stage Renal Failure

End Stage Kidney Disease

End Stage Renal Disease

End Stage Chronic Renal Failure

Esrf - [End Stage Renal Failure]

Esrd - [End Stage Renal Diseases]

Egfr - [Estimated Glomerular Filtration Rate] < 15 Ml/Min/1.73m²
Polycystic Kidney Disease

Polycystic Kidney Diseases

Pkd

Polycystic Renal Disease

Kidney Disease, Polycystic

Polycystic Kidney, Autosomal Dominant
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08865 MXRA5 Human Pre-designed siRNA Set A Pre-designed Set / 否
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