2. Gene
  3. Map3k4 - mitogen-activated protein kinase kinase kinase 4 Gene

Map3k4 - mitogen-activated protein kinase kinase kinase 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tas; MTK1; RP17; Mek4b; Mekk4; Rp17a; MEKK 4; D17Rp17; MAPKKK4; D17Rp17e; mKIAA0213

基因 ID: 26407 | 基因类型: protein coding

关于 Map3k4

功能概要

Enables protein kinase activity. Involved in intracellular signal transduction and positive regulation of JUN kinase activity. Acts upstream of or within several processes, including chorionic trophoblast cell differentiation; male germ-line sex determination; and placenta development. Located in cytoplasm. Is expressed in several structures, including central nervous system; future brain; and genitourinary system. Orthologous to human MAP3K4 (mitogen-activated protein kinase kinase kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Map3k4 基因产物(2)

mRNA Protein Name
NM_001357722.1 NP_001344651.1 mitogen-activated protein kinase kinase kinase 4 isoform 2
NM_011948.2 NP_036078.2 mitogen-activated protein kinase kinase kinase 4 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12878610 MGI
enables protein kinase activity IDA
IDA: 通过直接分析推断
16157600 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within chorionic trophoblast cell differentiation IMP
IMP: 通过突变表型推断
19289495 MGI
involved in intracellular signal transduction IDA
IDA: 通过直接分析推断
16157600 MGI
acts upstream of or within male germ-line sex determination IMP
IMP: 通过突变表型推断
6855886 MGI
acts upstream of or within placenta development IMP
IMP: 通过突变表型推断
19289495 MGI
involved in positive regulation of JUN kinase activity IDA
IDA: 通过直接分析推断
16157600 MGI
acts upstream of or within positive regulation of JUN kinase activity IMP
IMP: 通过突变表型推断
12878610 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
19289495 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16157600 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mitogen-activated protein kinase kinase kinase 4

MAPK/ERK kinase kinase 4

MEK kinase 4

T-associated sex reversal

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08057 MAP3K4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19516 Map3k4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26011 Map3k4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Map3k4 NCBI NCBI:4216
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