2. Gene
  3. Nr5a2 - nuclear receptor subfamily 5, group A, member 2 Gene

Nr5a2 - nuclear receptor subfamily 5, group A, member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ftf; LRH-1; UF2-H3B; D1Ertd308e

基因 ID: 26424 | 基因类型: protein coding

关于 Nr5a2

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; Cholesterol homeostasis; and pancreas morphogenesis. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; ear; early conceptus; and gonad. Orthologous to human NR5A2 (nuclear receptor subfamily 5 group A member 2). [provided by Alliance of Genome Resources, Apr 2022]

Nr5a2 基因产物(2)

mRNA Protein Name
NM_001159769.2 NP_001153241.1 nuclear receptor subfamily 5 group A member 2 isoform 2
NM_030676.3 NP_109601.1 nuclear receptor subfamily 5 group A member 2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
15014077 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
12456679 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
12456679 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
19389484 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within acinar cell differentiation IMP
IMP: 通过突变表型推断
25063451 MGI
acts upstream of or within bile acid metabolic process IMP
IMP: 通过突变表型推断
15014077 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
acts upstream of or within cholesterol homeostasis IMP
IMP: 通过突变表型推断
15014077 MGI
acts upstream of or within pancreas morphogenesis IMP
IMP: 通过突变表型推断
25063451 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
30555544 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
22977234 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12456679 MGI
involved in positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
19389484 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
15831456 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
20937355 MGI
acts upstream of or within regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
15684064 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of RNA polymerase II transcription regulator complex IDA
IDA: 通过直接分析推断
19389484 MGI
located in nucleus IDA
IDA: 通过直接分析推断
19796622 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear receptor subfamily 5 group A member 2

fetoprotein transcription factor

liver receptor homolog 1

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-115613 ML-180 Inhibitor 99.96% 否
HY-131445 RJW100 Activator 99.93% 否
HY-110329 ML179 Agonist 99.73% 否
HY-134462 RJW103 Agonist 98.71% 否
HY-RS09554 NR5A2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17146 Nr5a2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23595 Nr5a2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nr5a2 NCBI NCBI:2494
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z